Protein Alignment Cyp4d8 and cyp19a1

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001090630.1
• Gene: cyp19a1 / 100036594
• XenbaseID: XB-GENE-953895
• Length: 500
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 137/518 - (26%)
• Similarity: 229/518 - (44%)
• Gaps: 107/518 - (20%)

  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKVANLPGP-IC---PPLIGAMQLMLRLNPKTFI-KVGRE 60
            :.:|||::|     |        .:.:...:||| .|   .|||...:.:|     |.| |....
 Frog    28 LFIFLLIIL-----W--------NQEETCLIPGPAYCMGLGPLISYGRFLL-----TGIGKAANY 74

  Fly    61 YVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVY-KVLGQWLG--------NGLLL 116
            |...:|...||||       :|:..|.....|:..|::||..| ...|..||        ||::.
 Frog    75 YNNMYGEFVRVWI-------NGEETLVISKASATFHIMKHSHYISRFGSKLGLQCIGMNENGIIF 132

  Fly   117 -SDGKVWHQRRKIITPTFHFSI----LEQFVEVFDQQSNICVQRLAQKAN--GNTFDVYRSICAA 174
             |:..:|    |:|.|.|..::    |.|..|:..:.:...:..|....|  ||. ||.:.:...
 Frog   133 NSNPSLW----KVIRPFFIKALSGPGLMQTTEICIRSTKRYLDNLGNVTNELGNV-DVLKLMRLI 192

  Fly   175 ALDIIAETAMGTKIYAQANEST----PYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQ 235
            .||  ....:..:|....||..    .|.:|         |:  ::.|:.::.|.::..:.|:.:
 Frog   193 MLD--TSNNLFLRIPLDENEIVLKIQKYFDA---------WQ--ALLLKPDIFFKISWLYKKYEK 244

  Fly   236 TQLIRTMQEFTIKVIEKRRQALEDQQSKL---MDTADEDVGSKRRMALLDVLLMSTVDGRPLTND 297
            :  ...::|....:||::||.|...: ||   ||.|.|             |:.:...| .||.:
 Frog   245 S--ANDLKEAIEILIEQKRQKLSSSE-KLDENMDFASE-------------LIFAQNHG-DLTAE 292

  Fly   298 EIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYM 362
            .:.:.:...:....||.:.:|.|.|..:::||:::..::.||..|:|   .|.|...|:..||.:
 Frog   293 NVNQCILEMLIAAPDTMSVSLFFMLVLVAQHPKIEEGIMNEIDNVIG---DRDVESNDIPNLKVL 354

  Fly   363 ECVIKESLRMYPPVPIVGRK-LQTDFKYTHSVHGDG-VIPAGSEIIIGIFGVHRQPETFPNPDEF 425
            |..|.||:|..|.|.:|.|| |:.|..       || .:..|:.||:.:..:|| .|.||.|:||
 Frog   355 ENFIYESMRYQPVVDLVMRKALEDDMI-------DGYYVKKGTNIILNLGRMHR-IEYFPKPNEF 411

  Fly   426 IPERHENGSRVAPFKMI-PFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVNI 487
            ..|..|   :..|::.. ||.:|||.|.|:..|.:.||::|..:.:.|::..:|.|  |:.||
 Frog   412 TLENFE---KTVPYRYFQPFGSGPRACAGKYIAMVMMKVILVTLFKRYKVQTLGGR--CLENI 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	120/448 (27%)
cyp19a1	NP_001090630.1	p450	46..486	CDD:365848	132/487 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110