DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp316a1 and CYP86B1

DIOPT Version :9

Sequence 1:	NP_648129.2	Gene:	Cyp316a1 / 38840	FlyBaseID:	FBgn0035790	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_197710.1	Gene:	CYP86B1 / 832383	AraportID:	AT5G23190	Length:	559	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	115/540 - (21%)
Similarity:	208/540 - (38%)	Gaps:	103/540 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ILTATFICFCLASAFNYFRARRQRSLIKNLKGPFTWPLMGAMHKLLFLTPINFFQRSTEYL-TKY 65
            :|.|.|:       |....|.||    |..:|...||.:|.:..|.|....|.::..::.| .:.
plant    41 LLIAIFV-------FVAIHALRQ----KKYQGLPVWPFLGMLPSLAFGLRGNIYEWLSDVLCLQN 94

  Fly    66 GTFS--RCWVFHRLFIPLADLELSRQLLEN--DTHLETGY--ELMKDWLVGGVLMCQSEQWQKRH 124
            |||.  ..|..........|......||:|  ....:..|  :.::|.|..|:.....|.||::.
plant    95 GTFQFRGPWFSSLNSTITCDPRNVEHLLKNRFSVFPKGSYFRDNLRDLLGDGIFNADDETWQRQR 159

  Fly   125 SLISGLFDKGNLEQLIDLSRHQTEQLLQKLAKQ---------ADQKVFDIWYTVSPIVLDLMVMT 180
            ...|..|......||      .|:.|.:.:.|:         ......|:...:..:..|.:.|.
plant   160 KTASIEFHSAKFRQL------TTQSLFELVHKRLLPVLETSVKSSSPIDLQDVLLRLTFDNVCMI 218

  Fly   181 TCGA--------KPSEEYSKNLKDLSEIYRKRFLSLQSANRFNYWLSSPFMRKRQNRLIKRLNDE 237
            ..|.        :|...::|..:|.:|....||:......:|..:|... ..|:....||.::|.
plant   219 AFGVDPGCLGPDQPVIPFAKAFEDATEAAVVRFVMPTCVWKFMRYLDIG-TEKKLKESIKGVDDF 282

  Fly   238 HNNLMAMHQSQNQLKIENGLDIYQLRPIPLKDHKSLLEILLESKDPQLTGE--------EICGEL 294
            .:.::...:.:..|:.|.            .....||.:.:..:|.:  ||        :||
plant   283 ADEVIRTRKKELSLEGET------------TKRSDLLTVFMGLRDEK--GESFSDKFLRDIC--- 330

  Fly   295 NTCNYL--GYQLCSPALCFCLVTIARNPSVQQKCLDEL--NLAQIKDQG-------------WDL 342
              .|::  |....|.||.:....:.:||.|::|.:.|:  .|.|..|.|             .::
plant   331 --VNFILAGRDTSSVALSWFFWLLEKNPEVEEKIMVEMCKILRQRDDHGNAEKSDYEPVFGPEEI 393

  Fly   343 EKLNYLDAVLHETMRLYPPQVIVGRQLKKD--FPYTHSIVGDAELPCGSEIYINLYELQRNEVRY 405
            :|::||.|.|.|.:||||...:..:::::|  ||      ....|..|.::...:|.:.|.|..:
plant   394 KKMDYLQAALSEALRLYPSVPVDHKEVQEDDVFP------DGTMLKKGDKVIYAIYAMGRMEAIW 452

  Fly   406 PK-ANHFDAQRFL-------DSPPELLSYSLGPRCCPARKFSMQLLKTLLAPILANFEV-LPYGD 461
            .| ...|..:|:|       :|..:..:::.|||.|..:.|:...:|:..|.|:..::| :..|.
plant   453 GKDCLEFRPERWLRDGRFMSESAYKFTAFNGGPRLCLGKDFAYYQMKSTAAAIVYRYKVKVVNGH 517

  Fly   462 EVRLDLRLVLGSSNGFQLAL 481
            :|...|.|.:...:|..:.|
plant   518 KVEPKLALTMYMKHGLMVNL 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp316a1	NP_648129.2	p450	33..466	CDD:299894	103/492 (21%)
CYP86B1	NP_197710.1	PLN03195	38..541	CDD:215627	115/540 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53736
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.020