Protein Alignment Cyp316a1 and cyp4v2.2

DIOPT Version :10

• Sequence 1: NP_648129.2
• Gene: Cyp316a1 / 38840
• FlyBaseID: FBgn0035790
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_001072667.1
• Gene: cyp4v2.2 / 780124
• XenbaseID: XB-GENE-977085
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 529
• Identity: 127/529 - (24%)
• Similarity: 240/529 - (45%)
• Gaps: 74/529 - (13%)

  Fly     2 ILTATFICFCLASAF-NYFRARRQRSLIKNLKGPF-TWPLMGAMHKLLFL--TPINFFQRSTEYL 62
            ::..|.:...:..|. :|.|.||   ::|.:.||. .:||:|   ..|||  ...:||.:..||.
 Frog    17 VVLLTLLALSILPALQDYVRKRR---ILKPIPGPGPNYPLIG---DALFLKNNGGDFFLQICEYT 75

  Fly    63 TKY--GTFSRCWVFHRLFIPLADLELSRQLLENDTHLETG--YELMKDWLVGGVLMCQSEQWQKR 123
            ..|  ....:.|:....||.:...:....:|.:..|::..  |:.:..||..|:|....|:|:.|
 Frog    76 ESYRLQPLLKVWIGTIPFIVVYHADTVEPVLSSSKHMDKAFLYKFLHPWLGKGLLTSTGEKWRSR 140

  Fly   124 HSLISGLFDKGNLEQLIDLSRHQTEQLLQKLAKQADQKVFDIWYTVSPIVLDLMVMTTCGAKPSE 188
            ..:|:..|....|.:.:::...|::.|::||....|.:.||.:..|:...||::..|..|.|...
 Frog   141 RKMITPTFHFAILSEFLEVMNEQSKILVEKLQTHVDGESFDCFMDVTLCALDIISETAMGRKIQA 205

  Fly   189 EYSKNLKDLSEIYRKRFLSLQSANRFNY-WLSSPFMRKRQNRLIKRLNDEHN-NLMAMHQSQNQL 251
            :.:::.:.:..||:...: :|...:..: ||...:...|..:       ||: ||..:|...::.
 Frog   206 QSNRDSEYVQAIYKMSDI-IQRRQKMPWLWLDFLYAHLRDGK-------EHDKNLKILHSFTDKA 262

  Fly   252 KIENGLDIYQL---------------RPIPLKDHKSLLEILLESKDP---QLTGEEICGELNTCN 298
            .:|...::.::               :|   |...:.|::||.:.|.   :::..:|..|::|..
 Frog   263 ILERAEELKKMGEQKKEHCDSDPESDKP---KKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFM 324

  Fly   299 YLGYQLCSPALCFCLVTIARNPSVQQKCLDELNLAQIKDQGW----------DLEKLNYLDAVLH 353
            :.|:...:.||.:.|..:..:|..|::...||      |:.:          ||:||.||:||:.
 Frog   325 FEGHDTTAAALNWSLFLLGSHPEAQRQVHKEL------DEVFGKSDRPVTMDDLKKLRYLEAVIK 383

  Fly   354 ETMRLYPPQVIVGRQLKKDFPYTHSIVGDAELPCGSEIYINLYELQRNEVRYPKANHFDAQRFLD 418
            |::|:||...:.||.:.:|.    ||.| ..:|.|..:.|..|.|.|:...:|:...|..:||..
 Frog   384 ESLRIYPSVPLFGRTVTEDC----SIRG-FHVPKGVNVVIIPYALHRDPEYFPEPEEFRPERFFP 443

  Fly   419 ------SPPELLSYSLGPRCCPARKFSMQLLKTLLAPILANF--EVLPYGDEVRLDLRLVLGSSN 475
                  :|...:.:|.|.|.|..::|::...|.:|:.||.|:  |.....:|:.|...|:|...:
 Frog   444 ENASGRNPYAYIPFSAGLRNCIGQRFALMEEKVVLSSILRNYWVEASQKREELCLLGELILRPQD 508

  Fly   476 GFQLALKPR 484
            |..:.||.|
 Frog   509 GMWIKLKNR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp316a1	NP_648129.2	cytochrome_P450	70..479	CDD:477761	104/448 (23%)
cyp4v2.2	NP_001072667.1	CYP4V	70..512	CDD:410773	107/463 (23%)