Protein Alignment Cyp316a1 and Cyp4f37

DIOPT Version :10

• Sequence 1: NP_648129.2
• Gene: Cyp316a1 / 38840
• FlyBaseID: FBgn0035790
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_001093657.1
• Gene: Cyp4f37 / 677156
• MGIID: 3780112
• Length: 546
• Species: Mus musculus
• Alignment Length: 477
• Identity: 113/477 - (23%)
• Similarity: 208/477 - (43%)
• Gaps: 82/477 - (17%)

  Fly    56 QRSTEYLTKYGTFSRCWV-----FHRLFIP--LADLELSRQLL-ENDTHLETGYELMKDWLVGGV 112
            |..||....|.....||:     ..|:..|  :|.|.|:..|: ..||   |.:..:|.||..|:
Mouse    75 QLMTEAGQTYRDVHLCWLGPVIPVLRIVDPAFVAPLLLASALVAPKDT---TFHTFVKPWLGDGL 136

  Fly   113 LMCQSEQWQKRHSLISGLFDKGNLEQLIDLSRHQTEQLLQK---LAKQADQKVFDIWYTVSPIVL 174
            .:...::|.:...|::..|....|:..:.:.......:..|   |:.:...:: :::..:|.:.|
Mouse   137 FLNSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKHLSSEGSARL-EMFEHISLMTL 200

  Fly   175 DLMVM------TTCGAKPSEEYSKNLKDLSEIYRKR---------FLSLQSAN--RFN------Y 216
            |.:..      :.|...|| ||...:.:||.:..||         ||...:|:  ||.      :
Mouse   201 DSLQKCLFGFDSNCQESPS-EYISAILELSSLVIKRSHQLFLFVDFLYYHTADGRRFRKACDLVH 264

  Fly   217 WLSSPFMRKRQNRLIKRLNDEHNNLMAMHQSQNQLKIENGLDIYQLRPIPLKDHKSLLEILLESK 281
            ..:...:|:|::.|..:.:||      ..:|:.:.|.   ||              .:::||.:|
Mouse   265 NFTDAVIRERRHTLSSQNHDE------FLKSKTKSKT---LD--------------FIDVLLLAK 306

  Fly   282 D---PQLTGEEICGELNTCNYLGYQLCSPALCFCLVTIARNPSVQQKCLDE----LNLAQIKDQG 339
            |   .:|:.|:|..|.:|..:.|:...:.||.:.|..:||:|..|::|..|    |...:.::..
Mouse   307 DEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEIE 371

  Fly   340 W-DLEKLNYLDAVLHETMRLYPPQVIVGRQLKKDFPYTHSIVGDAE-LPCGSEIYINLYELQRNE 402
            | ||.:|.:|...:.|::||:||.:.:.|:..:|.     ::.|.. :|.|:...|:::.:..|.
Mouse   372 WDDLAQLPFLTMCIKESLRLHPPVIDLLRRCTRDI-----VLPDGRVIPKGNICVISIFGIHHNP 431

  Fly   403 VRYPKANHFDAQRF-----LDSPP-ELLSYSLGPRCCPARKFSMQLLKTLLAPILANFEVLPYGD 461
            ..:|....:|..||     ...|| ..:.:|.|||.|..:.|:|..:...||..|..|.:||...
Mouse   432 SVWPDPEVYDPFRFDPENAHKRPPLAFIPFSAGPRNCIGQTFAMNEMMVALALTLLRFRILPDDK 496

  Fly   462 EVRLDLRLVLGSSNGFQLALKP 483
            |.|....::|.:..|..|.::|
Mouse   497 EPRRKPEIILRAEGGLWLRVEP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp316a1	NP_648129.2	cytochrome_P450	70..479	CDD:477761	107/457 (23%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	111/472 (24%)