Protein Alignment Cyp316a1 and Cyp4a1

DIOPT Version :10

• Sequence 1: NP_648129.2
• Gene: Cyp316a1 / 38840
• FlyBaseID: FBgn0035790
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 116/480 - (24%)
• Similarity: 205/480 - (42%)
• Gaps: 59/480 - (12%)

  Fly    34 PFTW-----PLMGAMHKLLFLTPINFFQRSTEYLTKYGTFSRCWVFHRLFIPLADLELSRQLL-E 92
            ||.|     ...|.......:|.:..|.         ..|.|.:...:.::.:.|.:..:.:| .
  Rat    55 PFHWFFGHKQFQGDKELQQIMTCVENFP---------SAFPRWFWGSKAYLIVYDPDYMKVILGR 110

  Fly    93 NDTHLETGYELMKDWLVGGVLMCQSEQWQKRHSLISGLFDKGNLEQLIDLSRHQTEQLLQKLAKQ 157
            :|......|.|:..|:..|:|:...:.|.:...:::..|....|:..:.........:|.|..:.
  Rat   111 SDPKANGVYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWEQL 175

  Fly   158 ADQ-KVFDIWYTVSPIVLDLMVMTTCGAKPSEEYSKNLK-------DLSEIYRKRFLSLQSANRF 214
            |.| ...:|:..:|.:.||.::........|.:...|.|       :|::::..|..::...|..
  Rat   176 AGQDSSIEIFQHISLMTLDTVMKCAFSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDT 240

  Fly   215 NYWLSSP---FMRKRQNRLIKRLNDEHNNLMAMHQSQNQLKIENGLDIYQLRPIPLKDHKSLLEI 276
            .|..||.   |     ||..:..:|..:.::.:.:.|.|       :..:|..:..|.....|:|
  Rat   241 IYNFSSNGHLF-----NRACQLAHDHTDGVIKLRKDQLQ-------NAGELEKVKKKRRLDFLDI 293

  Fly   277 LL----ESKDPQLTGEEICGELNTCNYLGYQLCSPALCFCLVTIARNPSVQQKCLDELN--LAQI 335
            ||    |:.| .|:.:::..|::|..:.|:...:..:.:....:|.:|..||:|.:|:.  |...
  Rat   294 LLLARMENGD-SLSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGDG 357

  Fly   336 KDQGWD-LEKLNYLDAVLHETMRLYPPQVIVGRQLKKD--FPYTHSIVGDAELPCGSEIYINLYE 397
            ....|| |:::.|....:.|.:|||||...:.|:|...  ||...|      ||.|.::.:::|.
  Rat   358 SSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRS------LPKGIQVTLSIYG 416

  Fly   398 LQRNEVRYPKANHFDAQRFL-DSP---PELLSYSLGPRCCPARKFSMQLLKTLLAPILANFEVLP 458
            |..|...:|....||..||. |||   ...|.:|.|.|.|..::|:|..:|.::|..|..||:||
  Rat   417 LHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLP 481

  Fly   459 YGDEVRLDL-RLVLGSSNGFQLALK 482
            ...:|.:.| ||||.|.||..|.||
  Rat   482 DPTKVPIPLPRLVLKSKNGIYLYLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp316a1	NP_648129.2	cytochrome_P450	70..479	CDD:477761	106/434 (24%)
Cyp4a1	NP_787031.1	CYP4B-like	71..504	CDD:410771	109/460 (24%)