Protein Alignment Cyp316a1 and Cyp4e2

DIOPT Version :10

• Sequence 1: NP_648129.2
• Gene: Cyp316a1 / 38840
• FlyBaseID: FBgn0035790
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 126/547 - (23%)
• Similarity: 224/547 - (40%)
• Gaps: 93/547 - (17%)

  Fly     1 MILTATFICFCLASAFNYFRARRQRSLIKNLKGPFTWPLMGAMHKL------LFLTPINFFQR-- 57
            :.|....:.:...|.|      |:|.::....||...||||..|::      :..|..:::.:
  Fly     9 LALPLLLVAYLELSTF------RRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQYG 67

  Fly    58 STEYLTKYGTFSRCWVFHRLFIPLADLELSRQLLENDTHLETGYELMKDWLVGGVLMCQSEQWQK 122
            ...::...||:|...|....::   :..||.|.|...:.:   |:|...||..|:|.....:|.|
  Fly    68 KDNFVFWIGTYSNVLVTSSKYL---EFILSSQTLITKSDI---YQLTHPWLGLGLLTSTGSKWHK 126

  Fly   123 RHSLISGLFDKGNLEQLIDLSRHQTEQLLQKL-AKQADQKVFDIWYTVSPIVLDLMVMTTCGA-- 184
            ...:|:..|....|:...::....:.:.::.| ...|...:||.......:.||::..|..|.
  Fly   127 HRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSI 191

  Fly   185 KPSEEYSKNL----KDLSEIYRKRFLSLQSANRFNYWLSSPFMRKRQNRLIKRLNDEHNNLMAMH 245
            ...|..|.::    ||:......|.......|...|.|:..:  ...:|.:|.|.|..|.::|.
  Fly   192 NAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDY--PAYSRTLKTLQDFTNEIIAK- 253

  Fly   246 QSQNQLKIE---------NGLDIYQLRPIPLKDHKSLLEILLESKDPQLTGEEICGELNTCNYLG 301
                  :||         |..|.:..:.:...|  :||...::.:  .|..:|:..|::|..:.|
  Fly   254 ------RIEAHKSGAVSTNAGDEFTRKKMAFLD--TLLSSTIDGR--PLNSKELYEEVSTFMFEG 308

  Fly   302 YQLCSPALCFCLVTIARNPSVQQKCLDEL-----NLAQIKDQGW-DLEKLNYLDAVLHETMRLYP 360
            :...:..:.|.:..::|:...|:|...|.     |....:|..: ::.::.|||..:.|..|:||
  Fly   309 HDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYP 373

  Fly   361 PQVIVGRQLKKDFPYTHSIVGDAELPCGSEIYINLYELQRNEVRYPKANHFDAQRF-LDSPP--E 422
            ....:||..:||:    .|.||. :|.|:.:.:.|..|..||..:...:.|..:|| |:.|.  |
  Fly   374 SVPFIGRFTEKDY----VIDGDL-VPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGPFE 433

  Fly   423 LLSYSLGPRCCPARKFSMQLLKTLLAPILANFEVLPYGDEV------------------------ 463
            .:.:|.|||.|..:||::..:||:::.|:.||||||..||:
  Fly   434 YVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPY 498

  Fly   464 ------RLDLRLVLGSSNGFQLALKPR 484
                  .|...|.|.|.||..:.||.|
  Fly   499 RHKYDPILSAVLTLKSENGLYIRLKER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp316a1	NP_648129.2	cytochrome_P450	70..479	CDD:477761	107/463 (23%)
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	110/475 (23%)