Protein Alignment Cyp316a1 and CYP4B1

DIOPT Version :9

• Sequence 1: NP_648129.2
• Gene: Cyp316a1 / 38840
• FlyBaseID: FBgn0035790
• Length: 484
• Species: Drosophila melanogaster
• Sequence 2: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 118/415 - (28%)
• Similarity: 191/415 - (46%)
• Gaps: 56/415 - (13%)

  Fly   101 YELMKDWLVGGVLMCQSEQWQKRHSLISGLFDKGNLEQLIDLSRHQTEQLLQKLAKQA-DQKVFD 164
            |:....|:..|:|:.:..:|.:...|::..|....|:..:.:....|..:|.|..::| :.|.||
Human   115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFD 179

  Fly   165 IWYTVSPIVLDLMVMTT-------CGAKPSEEYSKNLKDLSEIYRKRFLSLQSANRFNYWLSSPF 222
            |:..|..:.|:.::..|       .|......|...:.||:.:.::|.:|.|..|.|.||| :|.
Human   180 IFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWL-TPH 243

  Fly   223 MRKRQNRLIKRLNDEHNNL--------MAMHQSQNQLKIENGLDIYQLRPIPLKDHKSLLEILLE 279
            .|    |.::.....|::.        .|:...:.:.||:|            :.|...|:|||.
Human   244 GR----RFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQN------------RRHLDFLDILLG 292

  Fly   280 SKDP---QLTGEEICGELNTCNYLGYQLCSPALCFCLVTIARNPSVQQKCLDELNLAQIKDQG-- 339
            ::|.   :|:..::..|::|..:.|:...:..:.:.|..:|..|..|.:|.:|:. ..:.||.
Human   293 ARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR-EILGDQDFF 356

  Fly   340 -W-DLEKLNYLDAVLHETMRLYPPQVIVGRQLKKDFPYTHSIVGDAELPCGSEIYINLYELQRNE 402
             | ||.|:.||...:.|:.|||||...|.|||.|  |.|  .|....||.||.|.:::|.|.||.
Human   357 QWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSK--PVT--FVDGRSLPAGSLISMHIYALHRNS 417

  Fly   403 VRYPKANHFDAQRFLDS------PPELLSYSLGPRCCPARKFSMQLLKTLLAPILANFEVLPYGD 461
            ..:|....||:.||...      |...:.:|.|||.|..::|:|..:|.:.|..|..||...  |
Human   418 AVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSL--D 480

  Fly   462 EVRLDLR---LVLGSSNGFQLALKP 483
            ..||.::   |||.|.|||.|.|||
Human   481 PSRLPIKMPQLVLRSKNGFHLHLKP 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp316a1	NP_648129.2	p450	33..466	CDD:299894	106/393 (27%)
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	114/409 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12533
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770