Protein Alignment mthl6 and ADGRG1

DIOPT Version :9

• Sequence 1: NP_788473.1
• Gene: mthl6 / 38839
• FlyBaseID: FBgn0035789
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: XP_005256294.1
• Gene: ADGRG1 / 9289
• HGNCID: 4512
• Length: 698
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 89/410 - (21%)
• Similarity: 141/410 - (34%)
• Gaps: 132/410 - (32%)

  Fly   131 LTDMIVLRYEFRYCEKVVSVQEDQYKLYENGSFMIKPDVNW----TLSK--QWY---CLHPRLED 186
            ||:.:||.::.:...|.|::|                .|.|    |||.  .|.   |...|.|.
Human   330 LTEPVVLTFQHQLQPKNVTLQ----------------CVFWVEDPTLSSPGHWSSAGCETVRRET 378

  Fly   187 PNSIWILEHVYIPKSMPAVPQVGTI--------SMVGCI-------LTIAVYL------------ 224
            ..|.:.....|....|.:..:|..:        |.|||:       :|||.||
Human   379 QTSCFCNHLTYFAVLMVSSVEVDAVHKHYLSLLSYVGCVVSALACLVTIAAYLCSRVPLPCRRKP 443

  Fly   225 ---YIKKLRNLLGKCFICYVFCKFVQYLIWAGGDLNLWNNICSLAGYTNYFFALASHFWLSVMSH 286
               .||...|||...|:........:.:...|.:..     |..:....:|..|....|:.:..:
Human   444 RDYTIKVHMNLLLAVFLLDTSFLLSEPVALTGSEAG-----CRASAIFLHFSLLTCLSWMGLEGY 503

  Fly   287 QIWKNLRLINRDERSY---HFLIYNIYGWGTPAIMTAITYLVD--------WAWEDRPDKLNWIP 340
            .::   ||:.....:|   :.|..:..|||.|..:..:..|||        .|....|:
Human   504 NLY---RLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPE------ 559

  Fly   341 GVGLY--RCWINTYDWSAMIYL--YGPMLILSLFNVVTFILTVNHIMKIKSSVKSSTQQQRKCIQ 401
            || :|  .|||..   |.:.|:  .|...::.|||:......|..|:::    :..||:.
Human   560 GV-IYPSMCWIRD---SLVSYITNLGLFSLVFLFNMAMLATMVVQILRL----RPHTQKW----- 611

  Fly   402 NNDFLLYLRLSVMMGVTGISEVITYFVKRHKFWRQVLRVPNFFHLGSG---IVVFVLFILKRSTF 463
             :..|..|.||:::|:.               |..:     ||...||   :||..||.:..| |
Human   612 -SHVLTLLGLSLVLGLP---------------WALI-----FFSFASGTFQLVVLYLFSIITS-F 654

  Fly   464 Q----------MIMERISGP 473
            |          |.::...||
Human   655 QGFLIFIWYWSMRLQARGGP 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403	17/74 (23%)
		7tm_4	211..398	CDD:304433	49/231 (21%)
ADGRG1	XP_005256294.1	GPS	349..393	CDD:280071	12/59 (20%)
		7tm_4	408..659	CDD:304433	66/299 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900