Protein Alignment mthl6 and adgre5b.3

DIOPT Version :9

• Sequence 1: NP_788473.1
• Gene: mthl6 / 38839
• FlyBaseID: FBgn0035789
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: XP_005160275.1
• Gene: adgre5b.3 / 792970
• ZFINID: ZDB-GENE-121214-275
• Length: 756
• Species: Danio rerio
• Alignment Length: 576
• Identity: 107/576 - (18%)
• Similarity: 207/576 - (35%)
• Gaps: 193/576 - (33%)

  Fly    15 SSQSEAVIPGCDYF-DTVDISHIPK---------------LNDSYAYEELIIPAHLTG------- 56
            ::||:.:...||.| ...|..:.|:               |||.:.       .|.|.
Zfish   191 NNQSKCIEMSCDQFKPEPDAGNTPEKLKHLMSLLMNSCKSLNDPHG-------EHFTAEKLLENL 248

  Fly    57 ------LYTFRQLADGSQ-----EPVKSHLRACICKLKPCIRFCCPRNKM-MPNSRCSDGLTENL 109
                  |.:...:|||..     :.|::.:|....:||.      |..|| ..|:.....:|.|
Zfish   249 CNSTDDLLSEGNVADGETLSVFLDAVENSMRLIGPQLKD------PVTKMETQNTYAEVAVTRN- 306

  Fly   110 KRINPYLKITLEDGT----------IGKYY-------LLT--DMIVLRYEFRYCEKVVS-VQEDQ 154
             :..|...:||..|:          :||.|       |::  ||......|....:..| |:|.|
Zfish   307 -QTPPSGSVTLSTGSAHFNTSWETVVGKSYPGFAFVALVSYKDMNSSSDLFNSMAREKSDVKEKQ 370

  Fly   155 --YKLYEN--GSFMIKPD----------------------------VNWTLSKQWY--------- 178
              |||...  .:.:..||                            |.|:.|::.:
Zfish   371 ITYKLNSKVVTAVVSNPDTKHLSKPVTLIFTHEEKRAESEGVAYSCVYWSESERGWSGRGCELAW 435

  Fly   179 ---------CLHPRLEDPNSIWILEHVYIPK---SMPAVPQVG-TISMVGCILTIAVYLYIKKLR 230
                     |.|     .:|..:|..:|..:   .:..:.:|| .:|::..||.|..:.:.:.::
Zfish   436 SNSTHTACSCSH-----LSSFAVLMALYPVEDTFELVVITRVGLVLSLICLILCILTFRFCRSIQ 495

  Fly   231 NLLGKCFICYVFCKFVQYLIWAGGDLNLWNNI-CSLAGYTNYFFALASHFWLSVMSHQIWKNLRL 294
            .......:....|.|:..|::..|..:..|.: |::.....:||.|::..|:.:...|:::.:.|
Zfish   496 GTRNSIHLHLSVCLFIADLVFLCGISSTHNQVACAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVL 560

  Fly   295 INRDERSYHFLIYNIY----GWGTPAIMTAITYLVDWAWEDRPDKLNWIP-GVGLYR-CWINTYD 353
            :      :|..:.::|    |:|.|.::.:|:.:.             :| |.|..| ||::...
Zfish   561 V------FHTTLKHLYMYAVGYGVPLVIVSISAIA-------------VPKGYGTDRHCWLSLEG 606

  Fly   354 WSAMIYLYGPMLILSLFNVVTFILTV--------------NHIMKIKSSVKSSTQQQRKCIQNND 404
            : .::..:.|:.|:.:.|:..||:||              :.:.||:|.:.::..|  .|:....
Zfish   607 Y-LILSFFIPVCIIVILNITVFIITVWKLALKFSSLNPDLSKLHKIRSFLATAVAQ--LCVLGGS 668

  Fly   405 FLLYLRLSVMMGVTGISEVITYFVKRHKFWRQVLRVPNFFHLGS--GIVVFVLFIL 458
            ::....|....|    :||:.|.               |..|.|  |.::|::..|
Zfish   669 WVFGFFLFQKNG----TEVMLYL---------------FIILNSLQGALIFIMHCL 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403	51/276 (18%)
		7tm_4	211..398	CDD:304433	39/207 (19%)
adgre5b.3	XP_005160275.1	EGF_CA	32..>62	CDD:214542
		EGF_CA	72..105	CDD:214542
		EGF_CA	<121..152	CDD:214542
		EGF_CA	154..188	CDD:214542
		GPS	416..460	CDD:197639	8/48 (17%)
		7tm_2	466..699	CDD:278432	51/273 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910