DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl6 and Adgrd1

DIOPT Version :9

Sequence 1:	NP_788473.1	Gene:	mthl6 / 38839	FlyBaseID:	FBgn0035789	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	XP_001070157.3	Gene:	Adgrd1 / 689257	RGDID:	1594795	Length:	903	Species:	Rattus norvegicus

Alignment Length:	385	Identity:	83/385 - (21%)
Similarity:	141/385 - (36%)	Gaps:	74/385 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 LTENLKRINPYLKITLEDGTIGKYYLLTDMIVLRYEFRYC--------EKVVSVQEDQYKLYENG 161
            |::||.. :|.:.:.|......|.|:.......|. |.||        |.|.|.|         |
  Rat   502 LSQNLSG-SPLITVHLRHKLTQKQYVDATNESNRL-FLYCAFLNFSSGEGVWSSQ---------G 555

  Fly   162 SFMIKPDVNWTLSKQWYCLHPRLEDPNSIWILEHVYIPKSMPAVPQV--GTISMVGC-------- 216
            ..:.:.::.:::.   :|.|     ..:..||..| :|..:....||  .:||.|||
  Rat   556 CALTEGNLTYSVC---HCTH-----LTNFAILMQV-VPLKLTLGHQVALSSISYVGCSLSVLCLA 611

  Fly   217 --ILTIAVYLYIKKLRNLLGKCFICYVFCKFV-QYLIWAGGDLNLWNNICSLAGYTNYFFALASH 278
              ::|.||...:..:||..........|...| |.|:.....:......|.:.....::|.|.:.
  Rat   612 ATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFSMEPGTVPCQVLAVLLHYFFLTAF 676

  Fly   279 FWLSVMSHQIWKNLRLINRDERSYHFLIYNIYGWGTPAIMTAITYLVDWAWEDRPDKLNWIPGVG 343
            .|:.|....::..:..:...|.|.|...|.| |||.|.::..|:.      ....|..    |.|
  Rat   677 AWMLVEGLHLYSMVIKVFGSEDSKHLYYYGI-GWGCPLLICIISV------SSSMDSY----GTG 730

  Fly   344 LYRCWINTYDWSAMIYLY-GPMLILSLFNVVTFILTVNHIMKIKS-SVK-----SSTQQQRKCIQ 401
             ..||::..  |..|:.: ||.|::.:.|:|..:.....|..|.: |.|     |:.:...|.:.
  Rat   731 -DSCWLSVE--SGAIWAFVGPALLVIVVNIVILVAVTRVISHISTDSYKIHGDPSAFKLTAKAVA 792

  Fly   402 NNDFLLYLRLSVMMGVTGISEVITYFVKRHKFWRQVLRVPNFFHLGSGIVVFVLFILKRS 461
              ..|..|..|.:.||..:|:....|  ::.|        ...:...|:.:|:...|..|
  Rat   793 --VLLPILGTSWVFGVLAVSDRALVF--QYMF--------AILNSSQGLFIFLFHCLLNS 840

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403	20/99 (20%)
mthl6	NP_788473.1	7tm_4	211..398	CDD:304433	46/204 (23%)
Adgrd1	XP_001070157.3	LamG	<173..273	CDD:304605
		GPS	539..579	CDD:280071	8/56 (14%)
		7tm_4	595..831	CDD:304433	56/261 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810