Protein Alignment mthl6 and adgrf7

DIOPT Version :10

• Sequence 1: NP_788473.1
• Gene: mthl6 / 38839
• FlyBaseID: FBgn0035789
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: XP_073789637.1
• Gene: adgrf7 / 613165
• ZFINID: ZDB-GENE-041001-214
• Length: 704
• Species: Danio rerio
• Alignment Length: 553
• Identity: 98/553 - (17%)
• Similarity: 183/553 - (33%)
• Gaps: 183/553 - (33%)

  Fly     1 MLLNILAIILVFVISSQSEAVIPGCDYFDTVDI----------SHIPKLNDSYAYEELI--IPAH 53
            ||:||.::....:|   |::|:.  |:..||||          ..:.|.|.|.:....:  |...
Zfish   202 MLVNIASVSQNIII---SKSVME--DFLKTVDILVSNEATASWQSLTKENTSISLLSAVEDISNR 261

  Fly    54 LT-GLYTFRQLADGSQEPV-------KSHLRACICK------LKP---CIRFCCPRNKMMPNSRC 101
            || |.:|..|........|       ||:|.....:      |.|   .|......|.::|....
Zfish   262 LTEGSFTINQKYIELNRTVINNSYTGKSNLPNSATEILIPQILNPTSLTIIIFTTLNNILPTQDS 326

  Fly   102 SDGLTENLKRINPYLKITLEDGTIGKYYLLTDMIVLRYEFRYCEKVVSVQEDQ------------ 154
            ::|:.:...|||..|.:...:.|:.....:.|                 ..||
Zfish   327 ANGIVKPDMRINGDLVVVKANQTLHSISFVFD-----------------TTDQSLGNPQCVFWNF 374

  Fly   155 -YKLYENGSFMIKPDVNWTLSKQWYCLHPR----LEDPNSIWILEHVYIPKSMPAVPQVGTISMV 214
             ...:::....:||..|.|......|.|..    |..|.||..:...|             ::.:
Zfish   375 NLSAWDSTGCEVKPGRNETGIITCECNHTASFSILMSPFSIDHIAFAY-------------VTYI 426

  Fly   215 GCILTIAVYLYIKKLRNLLGKCFICYVFCKFVQYLIWAG---GDLNLWNNI-------------- 262
            |..:::|                 |.:.|..::.::|..   .|.:...::
Zfish   427 GVGISVA-----------------CLILCLIIEAIVWKAVRRNDTSYMRHVSIVNIAISLLIADV 474

  Fly   263 ------------------CSLAGYTNYFFALASHFWLSVMSHQI-WKNLRLINRDERSYHFLIYN 308
                              ||...:..:.|.||..||:.:.:..: ::.:.::::..|:...:|..
Zfish   475 CFIIGAAISKEQPTPADRCSSVVFFMHLFYLALFFWMLISALLLFYRVVMVLSQMSRAKMMVIAF 539

  Fly   309 IYGWGTPAIMTAITYLVDWAWEDRPDKLNWIPGVGLYRCWINTYDWSAMIYLYGPMLILSLFNVV 373
            :.|:|.|.:::.||.    |....|...     |....||:|..:...::....|.|.:...|:|
Zfish   540 LLGYGAPLLISVITV----ASTAGPQMY-----VSKQACWLNWNESRNLLAFVIPALTIVAINLV 595

  Fly   374 TFILTVNHIMKIKSSVKSSTQQQRK-------CIQNNDFLLYLRLSVMMGVT---GISEVITYFV 428
            .||:.:..|.|.::.  ::||...|       |:      .:...::..|:|   ||...::
Zfish   596 VFIVVLYKIFKRRAG--AATQPDWKNALVVARCV------AFFTPALACGITWGFGIGTTVS--- 649

  Fly   429 KRHKFWRQVLRVPNFFHLGSGIVVFVLFILKRS 461
                               :|:.|.|:|.|..|
Zfish   650 -------------------AGLFVHVVFALFNS 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Methuselah_N	25..195	CDD:429053	42/215 (20%)
		7tmB3_Methuselah-like	211..471	CDD:410632	48/297 (16%)
		TM helix 2	234..256	CDD:410632	3/24 (13%)
		TM helix 3	264..291	CDD:410632	6/27 (22%)
		TM helix 4	304..324	CDD:410632	6/19 (32%)
		TM helix 5	353..382	CDD:410632	6/28 (21%)
		TM helix 6	400..427	CDD:410632	4/29 (14%)
		TM helix 7	435..460	CDD:410632	5/24 (21%)
adgrf7	XP_073789637.1	None