DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl6 and adgrl2a

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:XP_021335387.1 Gene:adgrl2a / 57987 ZFINID:ZDB-GENE-000607-49 Length:1520 Species:Danio rerio


Alignment Length:297 Identity:67/297 - (22%)
Similarity:122/297 - (41%) Gaps:77/297 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   202 MPAVPQVG-TISMVGCILTIAVYLYIKKL---RNLLGKCFICYVFCKFVQYLIWAGGDLNLWNNI 262
            :..:.:|| .:|::...::|..:.:.:.|   ||.:.|.....:|...:.:||  |.|:......
Zfish   863 LSVISRVGIVVSLICLAMSIFTFCFFRGLQSDRNTIHKNLCINLFIAELIFLI--GIDMTEPKLA 925

  Fly   263 CS-LAGYTNYFFALASHFWLSVMSHQIWKNLRLINRDE---RSYHFLIYNIYGWGTPAIMTAITY 323
            || :||..:||| |||..|:.:...|::..|..:...|   |.|.::.    |:..||::..::.
Zfish   926 CSIIAGILHYFF-LASFAWMCLEGVQLYLMLVEVFESEYSRRKYFYMA----GYLLPAVVVGVSA 985

  Fly   324 LVDWAWEDRPDKLNWIPGVGLYR-CWI---NTYDWSAMIYLYGPMLILSLFNVVTFILTVNHIMK 384
            .||:.            ..|..: ||:   |.:.||    ..||:..:.:.|::..::|:..:||
Zfish   986 AVDFR------------SYGTKKACWLRMDNHFIWS----FIGPVTFIIMLNLIFLLITMYKMMK 1034

  Fly   385 IKSSVKSSTQQ------QRKC--IQNNDFLLY--------------LRLSVMMGVTGISEVITYF 427
            ..:|:|..:.:      .|.|  ..|:|...|              ..|..::|:|         
Zfish  1035 HSTSLKPDSSRLEHINNYRVCDGYYNSDLPGYEDNKPFIKSWVMGGFALLCLLGLT--------- 1090

  Fly   428 VKRHKFWRQVLRVPNFFHLGSGIVVFVLFILKRSTFQ 464
                  |...|    ||...|.:|:..||.: .:|||
Zfish  1091 ------WSFGL----FFISESSVVLAYLFTI-FNTFQ 1116

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403
7tm_4 211..398 CDD:304433 46/203 (23%)
adgrl2aXP_021335387.1 Gal_Lectin 61..141 CDD:307994
OLF 155..411 CDD:321983
HormR 482..545 CDD:214468
GAIN 555..776 CDD:318649
GPS 800..851 CDD:197639
7tm_GPCRs 860..1141 CDD:333717 67/297 (23%)
TM helix 1 863..887 CDD:320095 4/23 (17%)
TM helix 2 896..917 CDD:320095 5/22 (23%)
TM helix 3 927..949 CDD:320095 10/22 (45%)
TM helix 4 968..984 CDD:320095 4/19 (21%)
TM helix 5 1003..1026 CDD:320095 6/26 (23%)
TM helix 6 1074..1099 CDD:320095 7/43 (16%)
TM helix 7 1103..1128 CDD:320095 6/15 (40%)
Latrophilin 1140..1520 CDD:308136
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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