DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl6 and adgre10

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:XP_021333746.1 Gene:adgre10 / 569655 ZFINID:ZDB-GENE-090313-152 Length:690 Species:Danio rerio


Alignment Length:294 Identity:59/294 - (20%)
Similarity:120/294 - (40%) Gaps:88/294 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   203 PAVPQVGTISMVGCILTIAVYLYIKKLRNLLGKCFICYVFCKFVQYLIWAGGDLNLWNNICSLAG 267
            |.|..|..|::  ||..::.:|.:     ||.:.|:..:..:.|..::              :||
Zfish   442 PGVNNVARINI--CISLLSAHLLL-----LLTQQFLSLIRPQQVLCVV--------------IAG 485

  Fly   268 YTNYFFALASHFWLSVMSHQIW---KNLRLIN---RDERSYHFLIYNIYGWGTPAIMTAITYLVD 326
            ..::.| |::..|:.:.:..::   |||..::   ::..|..||.  :.|:....|..:::    
Zfish   486 LLHFLF-LSAFVWMFIEAVLLFICVKNLSQVSSRKKEVLSNGFLC--VIGYVVALIGVSVS---- 543

  Fly   327 WAWEDRPDKLNWIP-GVGLYRCWINT---YDWSAMIYLYGPMLILSLFNVVTFI---LTVNHIMK 384
                     :..:| |.|..:|||..   :.||.:    ||:.::...||:.||   :.:|..:|
Zfish   544 ---------IGMVPEGYGSEQCWIKMDKGFFWSFL----GPVCVILGLNVILFISISIYLNSALK 595

  Fly   385 IKSSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVTGISEVITYFVKRHKFWRQVLRVP---NFF-H 445
             |.:.:.|..:|.|.:                   :.:.:..||        :|..|   .|| |
Zfish   596 -KLNAEVSQLKQTKVM-------------------VFKTLGQFV--------ILGCPWILGFFAH 632

  Fly   446 LGSGI-VVFVLFILKRSTFQMIMERI-SGPRRQQ 477
            :...: :||::...::.||..::..: |...|||
Zfish   633 VNMVVEIVFIIINSQQGTFIFLIYCVLSTEIRQQ 666

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403
7tm_4 211..398 CDD:304433 40/199 (20%)
adgre10XP_021333746.1 GPS 360..406 CDD:197639
7tm_GPCRs 413..672 CDD:333717 59/294 (20%)
TM helix 1 413..437 CDD:320095
TM helix 2 446..467 CDD:320095 7/27 (26%)
TM helix 3 481..503 CDD:320095 5/36 (14%)
TM helix 4 527..543 CDD:320095 4/17 (24%)
TM helix 5 561..584 CDD:320095 6/26 (23%)
TM helix 6 608..631 CDD:320095 6/49 (12%)
TM helix 7 635..660 CDD:320095 4/24 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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