DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl6 and adgrl1a

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:XP_021330394.1 Gene:adgrl1a / 562531 ZFINID:ZDB-GENE-131127-267 Length:1524 Species:Danio rerio


Alignment Length:337 Identity:69/337 - (20%)
Similarity:137/337 - (40%) Gaps:92/337 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 NPYLKITLEDGTIGKYYLLTDMIVLRYEFRYCEKVVSVQEDQYKLY--ENGSFMIK--------- 166
            |..:|:.:|.|..|:...:...::          ..|:.::..:::  |...|.::         
Zfish   736 NATVKMEMEAGIGGRGLAVNSHVI----------AASINKESSRVFLTEPVVFTLRHLQLENHFS 790

  Fly   167 PDVN-WTLSK-----QWYCLHPRLEDPNS--------------IWILEHV--YIPKSMP-----A 204
            |:.: |..|:     ||.....||.:.||              :.::.|.  | |..|.     .
Zfish   791 PNCSFWNYSERSMTGQWSSQGCRLIETNSTHTTCSCSHLTNFAVLMVHHEPDY-PGRMHELILFV 854

  Fly   205 VPQVG-TISMVGCILTIAVYLYIKKL---RNLLGKCFICYVFCKFVQYLIWAGGDLNLWNNICSL 265
            :..|| .||:|...:.|:.:.:::.|   ||.:.|.....:|...:.:||  |.|...::..|.:
Zfish   855 ITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFIAELLFLI--GIDKTQYHIACPI 917

  Fly   266 -AGYTNYFFALASHFWLSVMSHQIWKNLRLINRDERSY-HFLIYNIYGWGTPAIMTAITYLVDWA 328
             ||..::|| ||:..|:.:...|::  |.|:...|..| ....|.:.|:..||::..|:..:|  
Zfish   918 FAGLLHFFF-LAAFSWMCLEGIQLY--LMLVEVFESEYSRKKYYYLCGYCFPALVVGISAAID-- 977

  Fly   329 WEDRPDKLNWIPGVGLYR-------CWI---NTYDWSAMIYLYGPMLILSLFNVVTFILTVNHIM 383
                            ||       ||:   |.:.||    ..||:..:.:.|:|..::|::.::
Zfish   978 ----------------YRSYGTKKACWLRVDNYFIWS----FIGPVSFIIMLNLVFLMITLHKMI 1022

  Fly   384 KIKSSVKSSTQQ 395
            :..|::|..:.:
Zfish  1023 RNSSALKPDSSR 1034

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403 18/116 (16%)
7tm_4 211..398 CDD:304433 46/200 (23%)
adgrl1aXP_021330394.1 Gal_Lectin 48..128 CDD:307994
OLF 142..398 CDD:321983
HormR 474..535 CDD:214468
GAIN 545..765 CDD:318649 6/38 (16%)
GPS 789..836 CDD:197639 9/46 (20%)
7tmB2_Latrophilin-1 849..1106 CDD:320673 48/213 (23%)
TM helix 1 851..876 CDD:320673 6/24 (25%)
TM helix 2 885..907 CDD:320673 6/23 (26%)
TM helix 3 916..943 CDD:320673 8/29 (28%)
TM helix 4 955..975 CDD:320673 5/19 (26%)
TM helix 5 992..1021 CDD:320673 8/32 (25%)
TM helix 6 1037..1064 CDD:320673
TM helix 7 1068..1093 CDD:320673
Latrophilin 1105..1524 CDD:308136
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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