DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment mthl6 and Adgrg5

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:NP_001139444.1 Gene:Adgrg5 / 382045 MGIID:2685955 Length:524 Species:Mus musculus


Alignment Length:292 Identity:63/292 - (21%)
Similarity:107/292 - (36%) Gaps:92/292 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   185 EDPNSIWILEH----VYIPKSM-------PAVPQVGT--ISMVGC-------ILTIAVYLYIKKL 229
            |.|::..:|.|    .|....|       ||..||..  ||.|||       :|||.:|...:|.
Mouse   208 EQPSATQVLCHCNHLTYFAVL
MQLSGDPVPAELQVPLEYISFVGCSISIVASLLTILLYAQSRKQ 272

  Fly   230 --------RNLLGKCFICYVFCKFVQYLIWAGGDL-NLWNNICSLAGYTNYFFALASHFWLSVMS 285
                    .||.|.     |....|.:|:.:...| .:...:|.:.....::..|:|..|:::..
Mouse   273 SDSTTRIHMNLNGS-----VLLLNVTFLLSSQMTLPTMPRPVCKVLAAVLHYALLSSLTWMAIEG 332

  Fly   286 HQIWKNLRLINRDERSYHFL--IYNIY-----------GWGTPAIMTAITYLV------------ 325
            ..:             |.||  :||.|           |||.||::..:..::            
Mouse   333 FNL-------------YLFLGRVYNAYIRRYLLKLCMLGWGFPALLVLLLLMIKSSVYGPCVTSL 384

  Fly   326 DWAWEDRPDKLNWIPGVGLYR---CWINT-YDWSAMIYLYGPMLILSLFNVVTFILTVNHIMKIK 386
            ..:.|:         |.|...   |||.: ...|.::..||.  ..||||:|.....:..:.:::
Mouse   385 SKSQEN---------GTGFQNVSMCWIRSPMVHSILVMGYGG--FTSLFNLVVLAWALWILCRLR 438

  Fly   387 SSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVT 418
            :..|:.:....:     |..:.|.|:|::|.|
Mouse   439 AREKALSPWAYR-----DTAMVLGLTVLLGTT 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403 4/15 (27%)
7tm_4 211..398 CDD:304433 47/231 (20%)
Adgrg5NP_001139444.1 GPS 184..228 CDD:366827 5/19 (26%)
7tm_GPCRs 242..514 CDD:391938 54/258 (21%)
TM helix 1 244..268 CDD:341315 9/23 (39%)
TM helix 2 277..298 CDD:341315 6/25 (24%)
TM helix 3 311..333 CDD:341315 3/21 (14%)
TM helix 4 353..369 CDD:341315 5/15 (33%)
TM helix 5 405..428 CDD:341315 8/24 (33%)
TM helix 6 449..474 CDD:341315 6/22 (27%)
TM helix 7 478..503 CDD:341315
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.