Protein Alignment mthl6 and mth

DIOPT Version :9

• Sequence 1: NP_788473.1
• Gene: mthl6 / 38839
• FlyBaseID: FBgn0035789
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_728521.1
• Gene: mth / 38058
• FlyBaseID: FBgn0023000
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 493
• Identity: 201/493 - (40%)
• Similarity: 300/493 - (60%)
• Gaps: 34/493 - (6%)

  Fly     1 MLLNILAIILVFVISSQSEAVIPGCDYFDTVDISHIPKL-NDSYAYEELIIPAHLTGLYTFRQLA 64
            ::|.|..:|||.::..:|.|.|..||||||||||...|| |.||.:|.|::||.|||.|.||.|.
  Fly     5 LVLRISTVILVVLVIQKSYADILECDYFDTVDISAAQKLQNGSYLFEGLLVPAILTGEYDFRILP 69

  Fly    65 DGSQEPVKSHLRACICKLKPCIRFCCPRNKMMPNSRCSDGLT-ENLKRINPYLKITLEDGTIGKY 128
            |.|::.|..|:|.|:||||||:|||||.:.:|.|..|.|.:: |.|..::|:|.:||:||::.:.
  Fly    70 DDSKQKVARHIRGCVCKLKPCVRFCCPHDHIMDNGVCYDNMSDEELAELDPFLNVTLDDGSVSRR 134

  Fly   129 YLLTDMIVLRYEFRY-CEKVVSV----QEDQYKLYENGSFMIKPDVNWTLSKQWYCL-HPRLEDP 187
            :...::|| :::... |:.:..:    ::|:|.|:|||:|....| ..||.|:.||| |....|.
  Fly   135 HFKNELIV-QWDLPMPCDGMFYLDNREEQDKYTLFENGTFFRHFD-RVTLRKREYCLQHLTFADG 197

  Fly   188 N--SIWILEH--VYIPKSMPAVPQVGTISMVGCILTIAVYLYIKKLRNLLGKCFICYVFCKFVQY 248
            |  ||.|..|  :.:| |:.....|...|::..:|||||||::|||:||.|||||||:.|.|:.|
  Fly   198 NATSIRIAPHNCLIVP-SITGQTVVMISSLICMVLTIAVYLFVKKLQNLHGKCFICYMVCLFMGY 261

  Fly   249 LIWAGGDLNLWN---NICSLAGYTNYFFALASHFWLSVMSHQIWKNLR----LINRDERSYHFLI 306
            |...   |:||.   :.|..||:..|||.:|:.|||||:|..:|...|    ..||....:.||.
  Fly   262 LFLL---LDLWQISISFCKPAGFLGYFFVMAAFFWLSVISLHLWNTFRGSSHKANRFLFEHRFLA 323

  Fly   307 YNIYGWGTPAIMTAITYLVDWAWEDRPDKLNWIPGVGLY-RCWINTYDWSAMIYLYGPMLILSLF 370
            ||.|.||...::|.||.|.|...|::    :|.|.||.. .|||.|..||||:|.||||:.|..|
  Fly   324 YNTYAWGMAVVLTGITVLADNIVENQ----DWNPRVGHEGHCWIYTQAWSAMLYFYGPMVFLIAF 384

  Fly   371 NVVTFILTVNHIMKIKSSVKS-STQQQRKCIQNND---FLLYLRLSVMMGVTGISEVITYFVKRH 431
            |:..||||...|:.:|..::: :.:|:||...|:|   :..:|||.::||::...|:.:||.:.:
  Fly   385 NITMFILTAKRILGVKKDIQNFAHRQERKQKLNSDKQTYTFFLRLFIIMGLSWSLEIGSYFSQSN 449

  Fly   432 KFWRQVLRVPNFFHLGSGIVVFVLFILKRSTFQMIMER 469
            :.|..|..|.::.:...||::|:||:|||||::::.||
  Fly   450 QTWANVFLVADYLNWSQGIIIFILFVLKRSTWRLLQER 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403	79/183 (43%)
		7tm_4	211..398	CDD:304433	84/195 (43%)
mth	NP_728521.1	Methuselah_N	29..209	CDD:284145	79/181 (44%)
		7tm_4	219..416	CDD:304433	87/203 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I4416
eggNOG	1	0.900	-	-		E1_KOG4193
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5395
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25921
OrthoDB	1	1.010	-	-		D111500at6656
OrthoFinder	1	1.000	-	-		FOG0003851
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47154
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.980