DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl6 and Adgrl1

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:XP_030099484.1 Gene:Adgrl1 / 330814 MGIID:1929461 Length:1543 Species:Mus musculus


Alignment Length:280 Identity:61/280 - (21%)
Similarity:115/280 - (41%) Gaps:71/280 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   202 MPAVPQVG-TISMVGCILTIAVYLYIKKL---RNLLGKCFICYVFCKFVQYLIWAGGDLNLWNNI 262
            :..:..|| .||:|...:.|:.:.:::.|   ||.:.|.....:|...:.:|:  |.|...:...
Mouse   931 LSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLV--GIDKTQYEVA 993

  Fly   263 CSL-AGYTNYFFALASHFWLSVMSHQIWKNLRLINRDERSY-HFLIYNIYGWGTPAIMTAITYLV 325
            |.: ||..:||| ||:..||.:....::  |.|:...|..| ....|.:.|:..||::..|...:
Mouse   994 CPIFAGLLHYFF-LAAFSWLCLEGVHLY--LLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAI 1055

  Fly   326 DWAWEDRPDKLNWIPGVGLYR-------CWI---NTYDWSAMIYLYGPMLILSLFNVVTFILTVN 380
            |                  ||       ||:   |.:.||    ..||:..:.:.|:|..::|::
Mouse  1056 D------------------YRSYGTEKACWLRVDNYFIWS----FIGPVSFVIVVNLVFLMVTLH 1098

  Fly   381 HIMKIKSSVKSSTQQQRKCIQN--NDFLLYLRLSVMMGVT---GI------SEVITYFVKRHKFW 434
            .:::..|.:|..:.:    :.|  :..|..:.|..::|:|   |:      |.|:.|..      
Mouse  1099 KMIRSSSVLKPDSSR----LDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLF------ 1153

  Fly   435 RQVLRVPNFFHLGSGIVVFV 454
                   ..|:...|:.:||
Mouse  1154 -------TTFNAFQGVFIFV 1166

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403
7tm_4 211..398 CDD:304433 46/201 (23%)
Adgrl1XP_030099484.1 OLF 214..470 CDD:383019
PLN02550 491..>573 CDD:178165
HormR 548..611 CDD:214468
GAIN 621..845 CDD:374574
GPS 869..921 CDD:197639
7tmB2_Latrophilin-1 928..1185 CDD:320673 61/280 (22%)
TM helix 1 931..955 CDD:320673 6/23 (26%)
TM helix 2 964..985 CDD:320673 4/22 (18%)
TM helix 3 995..1017 CDD:320673 9/22 (41%)
TM helix 4 1036..1052 CDD:320673 4/15 (27%)
TM helix 5 1071..1094 CDD:320673 7/26 (27%)
TM helix 6 1118..1143 CDD:320673 5/24 (21%)
TM helix 7 1147..1172 CDD:320673 6/33 (18%)
Latrophilin 1185..1543 CDD:367050
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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