DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl6 and ADGRD1

DIOPT Version :9

Sequence 1:	NP_788473.1	Gene:	mthl6 / 38839	FlyBaseID:	FBgn0035789	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	NP_001317426.1	Gene:	ADGRD1 / 283383	HGNCID:	19893	Length:	906	Species:	Homo sapiens

Alignment Length:	204	Identity:	44/204 - (21%)
Similarity:	78/204 - (38%)	Gaps:	28/204 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 IPKSMPAVPQV--GTISMVGC----------ILTIAVYLYIKKLRNLLGKCFICYVFCKFV-QYL 249
            :|..:....||  .:||.|||          ::|.||...:..:||..........|...| |.|
Human   586 VPLELARGHQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVL 650

  Fly   250 IWAGGDLNLWNNICSLAGYTNYFFALASHFWLSVMSHQIWKNLRLINRDERSYHFLIYNIYGWGT 314
            :.....|......|.:.....::|.|::..|:.|....::..:..:...|.|.|...|.: |||.
Human   651 LLISFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGM-GWGF 714

  Fly   315 PAIMTAITYLVDWAWEDRPDKLNWIPGVGLYRCWINTYDWSAMIYLY-GPMLILSLFNVVTFILT 378
            |.::..|:  :.:|.:......|         ||::..  |..|:.: .|.|.:.:.|:...|..
Human   715 PLLICIIS--LSFAMDSYGTSNN---------CWLSLA--SGAIWAFVAPALFVIVVNIGILIAV 766

  Fly   379 VNHIMKIKS 387
            ...|.:|.:
Human   767 TRVISQISA 775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403
mthl6	NP_788473.1	7tm_4	211..398	CDD:304433	41/189 (22%)
ADGRD1	NP_001317426.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810