DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl6 and Adgrg2

DIOPT Version :9

Sequence 1:	NP_788473.1	Gene:	mthl6 / 38839	FlyBaseID:	FBgn0035789	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	NP_852031.1	Gene:	Adgrg2 / 266735	RGDID:	628618	Length:	1013	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	63/248 - (25%)
Similarity:	105/248 - (42%)	Gaps:	52/248 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 PKSMPAVPQVGTISMVGCIL-------TIAVYLYIKKL-RNLLGKCFICYVFCKFVQYLIWAGGD 255
            |..|.|:.   .|:.:||.|       |:..|:..:|: |:...|..|.......:..|::.
  Rat   618 PSQMMALT---FITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFL--- 676

  Fly   256 LNLW------NNIC-SLAGYTNYFFALASHFWLSVMS-HQIWKNLRLINRDERSYHFLIYNIYGW 312
            |:.|      ...| |:|.:.:||. |.|..|:.:.: |.....:::.|...|.| .|.:.|.||
  Rat   677 LDSWIALYNARGFCISVAVFLHYFL-LVSFTWMGLEAFHMYLALVKVFNTYIRKY-ILKFCIVGW 739

  Fly   313 GTPAIMTAITYLVDWAWEDRPDKLNWIPGVGLYR----------CWINTYDWSAMIYL--YGPML 365
            |.||::.:|...:.      ||..    |:|.|.          ||||:   |.:.|:  .|...
  Rat   740 GIPAVVVSIVLTIS------PDNY----GIGSYGKFPNGTPDDFCWINS---SVVFYITVVGYFC 791

  Fly   366 ILSLFNVVTFILTVNHIMKIKSSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVT 418
            ::.|.||..||:.:..:.:||.. |....|::..||  |......|:.::|:|
  Rat   792 VIFLLNVSMFIVVLVQLCRIKKK-KQLGAQRKTSIQ--DLRSIAGLTFLLGIT 841

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403
mthl6	NP_788473.1	7tm_4	211..398	CDD:304433	54/214 (25%)
Adgrg2	NP_852031.1	GPS	566..608	CDD:280071
Adgrg2	NP_852031.1	7tm_4	621..871	CDD:304433	62/245 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810