Protein Alignment mthl6 and ADGRG3

DIOPT Version :9

• Sequence 1: NP_788473.1
• Gene: mthl6 / 38839
• FlyBaseID: FBgn0035789
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: XP_005255899.1
• Gene: ADGRG3 / 222487
• HGNCID: 13728
• Length: 596
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 94/476 - (19%)
• Similarity: 170/476 - (35%)
• Gaps: 163/476 - (34%)

  Fly    35 HIPKLNDSYAYEELII-----PAHLTGLYTFRQLADGSQEPVKSHLRACICKLKPCIRFCCPRNK 94
            |:.||.:..   |::.     |.::|....|..:..|:.....|  ..|..:::|....||
Human   190 HVTKLAEPL---EIVFSHQRPPPNMTLTCVFWDVTKGTTGDWSS--EGCSTEVRPEGTVCC---- 245

  Fly    95 MMPNSRCSDGLTENLKRINPYLKITLEDGTIGKYYLLT---------DMI-----VLRYEFRY-- 143
                  | |.||.....:.|    ||:..|:   ::||         .||     ::.|.|..
Human   246 ------C-DHLTFFALLLRP----TLDQSTV---HILTRISQAGCGVSMIFLAFTIILYAFLSPG 296

  Fly   144 ----------------------CEKVVSVQEDQYKLYENGSFMIKPDVNWTLSKQWYCLHPRLED 186
                                  ||:.:..||......:.|::.::      ||::.:    :.||
Human   297 LGHGPHPQQAECDLPAGRIAGPCERGLERQEKLPPAPQGGAWHLR------LSRERF----KSED 351

  Fly   187 PNSIWILEHVYIPKSMPAVPQVGTISMVGCILTIAVYLYIKKLRNLLGKCFICYVFCKFVQYLIW 251
            ...|    ||.:..|:             .:|.:|                          :|:.
Human   352 APKI----HVALGGSL-------------FLLNLA--------------------------FLVN 373

  Fly   252 AGGDLNLWNNICSLAGYTNYFFALASHFWLSVMSHQIWKNLRLINRDERSYHFLIYNIYGWGTPA 316
            .|......:..|...|...::|.|.:..|:.:.:..::.....:......::||..::.|||.||
Human   374 VGSGSKGSDAACWARGAVFHYFLLCAFTWMGLEAFHLYLLAVRVFNTYFGHYFLKLSLVGWGLPA 438

  Fly   317 IM-----TAITYLVDWAWEDRPDK----LNWI-PGVGLYRCWINTYDWSAMIYLYGPMLILSLFN 371
            :|     :|.:|.: :...||.::    |.|. .|..:|..:|..:.:..:.:|:| |::|:|
Human   439 LMVIGTGSANSYGL-YTIRDRENRTSLELCWFREGTTMYALYITVHGYFLITFLFG-MVVLAL-- 499

  Fly   372 VVTFILTVNHIMKIKSSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVTGISEVITYFVKRHKFWRQ 436
            ||..|.|::....:|...|:     ||.:     |..|.||.::|||               |..
Human   500 VVWKIFTLSRATAVKERGKN-----RKKV-----LTLLGLSSLVGVT---------------WGL 539

  Fly   437 VLRVPNFFHLG-SGIVVFVLF 456
            .:..|    || |.:.:|.||
Human   540 AIFTP----LGLSTVYIFALF 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403	38/204 (19%)
		7tm_4	211..398	CDD:304433	37/196 (19%)
ADGRG3	XP_005255899.1	GPS	213..255	CDD:280071	11/54 (20%)
		7tm_4	355..564	CDD:304433	58/278 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810