Protein Alignment mthl6 and Adgrg6

DIOPT Version :9

• Sequence 1: NP_788473.1
• Gene: mthl6 / 38839
• FlyBaseID: FBgn0035789
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: XP_006512741.1
• Gene: Adgrg6 / 215798
• MGIID: 1916151
• Length: 1258
• Species: Mus musculus
• Alignment Length: 559
• Identity: 110/559 - (19%)
• Similarity: 197/559 - (35%)
• Gaps: 205/559 - (36%)

  Fly     3 LNILAIILVFVISSQSEAVIPGCDYFDTVDISHIPKLNDSYAYEELIIPAHLTGLYTFRQLADGS 67
            :||....|...:||    :|||.:......|. :|..|:||...:               ..:|.
Mouse   680 VNIETQNLALGVSS----LIPGTNAPSNFSIG-LPSNNESYFQMD---------------FGNGQ 724

  Fly    68 QEPVKSHLRACICKLKPCIRFCCPRNKMMPNSRCSDGLTENLKRINPYLKITLEDGTIGKYYLLT 132
            .:|:.|.:                   :.||      |.|||   :|      ||
Mouse   725 TDPLASVI-------------------LPPN------LLENL---SP------ED---------- 745

  Fly   133 DMIVLRYEFRYCEKVVSVQE--DQYKLYEN-------GSFMIK---------------PDVN--- 170
            .::|.|.:|.:..|....|:  .|.|:..:       |:..|:               .:|:
Mouse   746 SVLVRRAQFTFFNKTGLFQDVGSQRKVLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPI 810

  Fly   171 ---WTLSKQ-----WY---CL-HPRLEDPNSIWILEH-------VYIPKSMPAVPQVGT-----I 211
               |.::|.     |.   |: |..|:...:|.:..|       :.:|:|...:....|     |
Mouse   811 CAFWDMNKNKSFGGWNTSGCVAHSDLDAGETICLCSHFTHFGVLMDLPRSASQIDGRNTKVLTFI 875

  Fly   212 SMVGC-------ILTIAVYLYIKKLR-----NLLGKCFICYVFCKFVQYLI--W------AGGDL 256
            :.:||       ..|:..|:..:|||     .:|.......:|...: :|:  |      ||
Mouse   876 TYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSSALLFLNLI-FLLDGWVTSFGVAG--- 936

  Fly   257 NLWNNICSLAGYTNYFFALASHFWLSVMS-HQIWKNLRLINRDERSYHFLIYNIYGWGTPAIMTA 320
                 :|:......:||.||:..|:.:.: |.....:::.|.....| .|.:.|.|||.||::.:
Mouse   937 -----LCTAVAALLHFFLLATFTWMGLEAIHMYIALVKVFNTYIHRY-ILKFCIIGWGLPALVVS 995

  Fly   321 I---------TYLVDWAWEDRPDKLNWIPGVGLYRCWINTYDWSAMIYL-----YGPMLILSLFN 371
            |         .|..:...:|:.|:.          |||..   ..:.|:     :|.|..|   |
Mouse   996 IILVSRRQNEVYGKESYGKDQDDEF----------CWIQD---PVVFYVSCAGYFGVMFFL---N 1044

  Fly   372 VVTFILTVNHIMKIKSSVKSSTQQQRKCIQNNDFLLYLR----LSVMMGVT-GISEVITYFVKRH 431
            |..||:.:..|.. ::..:|:...:.:.::|      ||    |:.::|:| |.:    :|.
Mouse  1045 VAMFIVVMVQICG-RNGKRSNRTLREEVLRN------LRSVVSLTFLLGMTWGFA----FFA--- 1095

  Fly   432 KFWRQVLRVPNFFHLGS------GIVVFVLFILKRSTFQ 464
              |.. |.:| |.:|.|      |:.:|:.....:...|
Mouse  1096 --WGP-LNIP-FMYLFSIFNSLQGLFIFIFHCAMKENVQ 1130

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403	35/217 (16%)
		7tm_4	211..398	CDD:304433	47/221 (21%)
Adgrg6	XP_006512741.1	CUB	48..156	CDD:238001
		LamG	188..347	CDD:389952
		HRM	543..588	CDD:382965
		GPS	809..854	CDD:366827	8/44 (18%)
		7tm_GPCRs	869..1137	CDD:391938	65/306 (21%)
		TM helix 1	871..896	CDD:341315	5/24 (21%)
		TM helix 2	906..928	CDD:341315	3/22 (14%)
		TM helix 3	939..966	CDD:341315	6/26 (23%)
		TM helix 4	981..997	CDD:341315	6/15 (40%)
		TM helix 5	1026..1049	CDD:341315	6/25 (24%)
		TM helix 6	1072..1097	CDD:341315	8/39 (21%)
		TM helix 7	1101..1126	CDD:341315	6/25 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810