DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl6 and Adgre1

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:NP_001342651.1 Gene:Adgre1 / 13733 MGIID:106912 Length:931 Species:Mus musculus


Alignment Length:250 Identity:63/250 - (25%)
Similarity:112/250 - (44%) Gaps:45/250 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   189 SIWILEHVYIPKSMPAVPQVGT-ISMVGCILTIAVYLYIKKLRNLLGKCFICYVFCKFVQYLIWA 252
            |::|:.|            ||| ||:|...|.||.:|..:.::|......:....|.|:..:::.
Mouse   646 SLYIISH------------VGTVISLVCLALAIATFLLCRAVQNHNTYMHLHLCVCLFLAKILFL 698

  Fly   253 GG-DLNLWNNICS-LAGYTNYFFALASHFWL---SVMSHQIWKNLRLINR-DERSYHFLIYNIYG 311
            .| |.......|: :||:.:|.| ||..||:   :||...:.:||:::|. ..|:...|....:|
Mouse   699 TGIDKTDNQTACAIIAGFLHYLF-LACFFWMLVEAVMLFLMVRNLKVVNYFSSRNIKMLHLCAFG 762

  Fly   312 WGTPAIMTAITYLVDWAWEDRPDKLNWIPGVGLY-RCWINT---YDWSAMIYLYGPMLILSLFNV 372
            :|.|.::..|:..|      :|      .|.|:: |||:||   :.||.:    ||:.::...|.
Mouse   763 YGLPVLVVIISASV------QP------RGYGMHNRCWLNTETGFIWSFL----GPVCMIITINS 811

  Fly   373 VTFILTVNHIMKIKSSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVTGISEVITYF 427
            |....|:..:.:...||.|...:.:     :..||..:....:.:.|.|.|:..|
Mouse   812 VLLAWTLWVLRQKLCSVSSEVSKLK-----DTRLLTFKAIAQIFILGCSWVLGIF 861

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403 3/7 (43%)
7tm_4 211..398 CDD:304433 51/196 (26%)
Adgre1NP_001342651.1 EGF_CA 33..63 CDD:238011
EGF_CA 81..115 CDD:214542
EGF_CA 133..172 CDD:214542
EGF_CA 173..>203 CDD:214542
EGF_CA 222..258 CDD:238011
EGF_CA 272..>301 CDD:214542
EGF_CA 319..352 CDD:214542
Cell attachment site. /evidence=ECO:0000255 506..508
GPS 591..640 CDD:197639
7tmB2_EMR 644..906 CDD:320555 62/249 (25%)
TM helix 1 646..671 CDD:320555 12/36 (33%)
TM helix 2 680..702 CDD:320555 3/21 (14%)
TM helix 3 711..738 CDD:320555 10/27 (37%)
TM helix 4 755..775 CDD:320555 5/19 (26%)
TM helix 5 792..815 CDD:320555 6/26 (23%)
TM helix 6 839..864 CDD:320555 5/22 (23%)
TM helix 7 868..893 CDD:320555
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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