DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mthl6 and LOC108181087

DIOPT Version :9

Sequence 1:	NP_788473.1	Gene:	mthl6 / 38839	FlyBaseID:	FBgn0035789	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	XP_021329169.1	Gene:	LOC108181087 / 108181087	-ID:	-	Length:	166	Species:	Danio rerio

Alignment Length:	180	Identity:	36/180 - (20%)
Similarity:	69/180 - (38%)	Gaps:	53/180 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   271 YFFALASHFWLSVMSHQIWKNLRLINRDERSYHFLIYNIYGWGTPAIMTAIT-------YLVDWA 328
            :.|.:|:..|:.|....:|..:..:|..| ..|...|.:.|||.|.::..||       |..|.
Zfish     2 HLFFMAAFSWMLVEGLLLWSKVVSVNLSE-DRHMKYYYLIGWGLPVLIVTITLASASGKYTADG- 64

  Fly   329 WEDRPDKLNWIPGVGLYRCWINTYD---WSAMIYLYGPMLILSLFNVVTFILTVNHIMKIKSSVK 390
                             .||::..:   |.    ..||::.:.:.|::  |||...::.|.::.:
Zfish    65 -----------------HCWLSVQNGVIWG----FAGPVIFIIMVNIM--ILTRVVVITIATAKR 106

  Fly   391 SS-------------TQQQRKCIQNNDFLLYLRLSVMMGVTGISEVITYF 427
            .|             ::|.|..::     ..|.|..::|:|.:..|:..|
Zfish   107 RSLMMALNNSPEEQISEQIRAAVK-----AVLVLLPILGLTWLCGVLVPF 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403
mthl6	NP_788473.1	7tm_4	211..398	CDD:304433	29/149 (19%)
LOC108181087	XP_021329169.1	7tm_GPCRs	<1..166	CDD:333717	36/180 (20%)
		TM helix 4	36..52	CDD:320095	5/15 (33%)
		TM helix 5	71..94	CDD:320095	5/28 (18%)
		TM helix 6	126..151	CDD:320095	6/29 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1153592at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010