Protein Alignment mthl6 and ADGRG2

DIOPT Version :9

• Sequence 1: NP_788473.1
• Gene: mthl6 / 38839
• FlyBaseID: FBgn0035789
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_001073327.1
• Gene: ADGRG2 / 10149
• HGNCID: 4516
• Length: 1017
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 70/296 - (23%)
• Similarity: 123/296 - (41%)
• Gaps: 66/296 - (22%)

  Fly   198 IPKSMPAVPQVGTISMVGCIL-------TIAVYLYIKKL-RNLLGKCFICYVFCKFVQYLIWAGG 254
            :|..|.|:.   .|:.:||.|       |:..|:..:|: |:...|..|.......:..|::.
Human   621 LPAQMMALT---FITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLLNLVFL-- 680

  Fly   255 DLNLW------NNIC-SLAGYTNYFFALASHFWLSVMS-HQIWKNLRLINRDERSYHFLIYNIYG 311
             |:.|      ..:| |:|.:.:||. |.|..|:.:.: |.....:::.|...|.| .|.:.|.|
Human   681 -LDSWIALYKMQGLCISVAVFLHYFL-LVSFTWMGLEAFHMYLALVKVFNTYIRKY-ILKFCIVG 742

  Fly   312 WGTPAIMTAITYLVDWAWEDRPDKLNWIPGVGLYR----------CWINTYDWSAMIYL--YGPM 364
            ||.||::..|...:.      ||..    |:|.|.          ||||.   :|:.|:  .|..
Human   743 WGVPAVVVTIILTIS------PDNY----GLGSYGKFPNGSPDDFCWINN---NAVFYITVVGYF 794

  Fly   365 LILSLFNVVTFILTVNHIMKIKSSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVT-GISEVITYFV 428
            .::.|.||..||:.:..:.:||.. |....|::..||  |......|:.::|:| |.:    :|.
Human   795 CVIFLLNVSMFIVVLVQLCRIKKK-KQLGAQRKTSIQ--DLRSIAGLTFLLGITWGFA----FFA 852

  Fly   429 KRHKFWRQV----LRVPNFFHLGSGIVVFVLFILKR 460
                 |..|    :.:...|:...|..:|:.:.:.:
Human   853 -----WGPVNVTFMYLFAIFNTLQGFFIFIFYCVAK 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl6	NP_788473.1	Mth_Ecto	25..197	CDD:119403
		7tm_4	211..398	CDD:304433	54/214 (25%)
ADGRG2	NP_001073327.1	GPS	569..612	CDD:280071
		7tm_4	625..875	CDD:304433	68/282 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810