DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl6 and adgrf11

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:XP_005160858.1 Gene:adgrf11 / 100537132 ZFINID:ZDB-GENE-121214-165 Length:691 Species:Danio rerio


Alignment Length:465 Identity:89/465 - (19%)
Similarity:161/465 - (34%) Gaps:122/465 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 SHIPKLNDSYAYEELIIPAHLT--------GLYTFRQLADGSQEP-VKSHLRACICKLKPCIRFC 89
            ||:|........::::.|..||        .:...|..|:|..:| |:.:....:.|:...::..
Zfish   240 SHLPNSTTEILIQQVLKPTSLTIIILTTLHSILPARYTANGKGKPDVRINGDVVVVKVNQTLQNI 304

  Fly    90 C----PRNKMMPNSRC-----------SDG--LTENLKRINPYLKITLEDGTIGKYYLL-----T 132
            .    ...:.:.|.:|           |.|  :..||.......|||.|......:.||     .
Zfish   305 SFVFDTTEQSLGNPQCVFWNFHLSTWDSTGCEVKPNLSEEEKIDKITCECNHTTSFSLLMSPFFI 369

  Fly   133 DMIVLRYEFRYCEKVVSVQEDQYKLYENGSFMIKPDVNWTLSKQWYCLHPRLEDPNSIWILEHVY 197
            |...|.| ..|....:||......|       |...:.||          .:...||.: |.|| 
Zfish   370 DDKALDY-ITYTGLGISVLSLVISL-------IIGAIVWT----------TVTKSNSAY-LRHV- 414

  Fly   198 IPKSMPAVPQVGTISMVGCILTIAVYLYIKKLRNLLGKCFICYVFCKFVQ--YLIWAGGDLNLWN 260
                              |::...|.|.:..:      |||  :....||  .|...|.      
Zfish   415 ------------------CLVNTNVSLLVADV------CFI--IGASIVQPGQLAPVGP------ 447

  Fly   261 NICSLAGYTNYFFALASHFWLSVMSH-QIWKNLRLINRDERSYHFLIYNIYGWGTPAIMTAITYL 324
              |:...::.:.|.||..||:.:.:. .::....:.::..|:....|....|:|.|.::..||| 
Zfish   448 --CTAVAFSMHLFFLAFFFWMLISAMLLLYMTTMVYSQMSRAKMMAIAFFLGYGAPLLIVVITY- 509

  Fly   325 VDWAWEDRPDKLNWIPGV----GLY-----RCWINTYDWSAMIYLYGPMLILSLFNVVTFILTVN 380
                            |:    |.|     .||:| :|.:..:.::  :.:.|.|..|..::.: 
Zfish   510 ----------------GLTAREGKYILEADVCWLN-FDETKALQIF--VSLASSFTAVNVLIII- 554

  Fly   381 HIMKIKSSVKSSTQQQRKCIQNNDFLLYLRLSVMMGVT---GISEVITYFVKRHKFWRQVLRVPN 442
             ::..|..:....|.:...|......:.|.:|.:.|||   ||..:::.....|..:..:..:..
Zfish   555 -VVLYKMLIVRKQQNKETNILPTVTRVVLIVSPLFGVTWGLGIGTMLSPDYGIHLVFTILNSLQG 618

  Fly   443 FFHLGSGIVV 452
            .|:|.||::|
Zfish   619 IFNLVSGLLV 628

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403 38/193 (20%)
7tm_4 211..398 CDD:304433 36/198 (18%)
adgrf11XP_005160858.1 GAIN 143..>227 CDD:293098
GPS 318..363 CDD:280071 9/44 (20%)
7tm_4 374..620 CDD:304433 59/321 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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