DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl6 and gpr157

DIOPT Version :9

Sequence 1:NP_788473.1 Gene:mthl6 / 38839 FlyBaseID:FBgn0035789 Length:480 Species:Drosophila melanogaster
Sequence 2:NP_001124512.1 Gene:gpr157 / 100038048 XenbaseID:XB-GENE-492646 Length:323 Species:Xenopus tropicalis


Alignment Length:312 Identity:64/312 - (20%)
Similarity:113/312 - (36%) Gaps:67/312 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   177 WYCLHPRLEDPNSIWILEHVYIPKSMPAVPQVGTISMVGCILTIAVYLYIKKLRNLLGKCFICYV 241
            |..: || ||.|   :.|.|.:..|.       .:|.:|..|.|..|:..:.||:......:...
 Frog     3 WLVI-PR-EDLN---VSEQVIVLLSC-------VLSFLGSALIIVTYILWQDLRSRPRLLLLFLS 55

  Fly   242 FCKFVQYLIWAGGDL-----NLWNNICSLAGYTNYFFALASHFWLSVMSHQIWKNLRLINRDERS 301
            ....:..|.:..|.|     :.|:  |...|..:.|...:|.||...::..::..   |.:.::|
 Frog    56 VADLLSALSYFYGVLRNFQDSTWD--CVTQGAISTFSNTSSFFWTVAVAVYLYIT---IVKSQQS 115

  Fly   302 YHFLI---YNIYGWGTPAIMTA-----------ITYL-VDWAWE--DRPDKLNWIPGVGLYRCWI 349
            :...|   .::..||.|.::|.           .:|: |.|.|.  |..|||.|:...|..    
 Frog   116 FADQIIPWLHLISWGVPLVITLSAVCLKKIGYDASYVSVGWCWVKIDVEDKLLWMLLAGKV---- 176

  Fly   350 NTYDWSAMIYLYGPMLILSLFNVVTFILTVNHIMKIKSS-------VKSSTQQQRKCIQNNDFLL 407
                |..:.||..|:|         :||...||.:..::       :.:|...|.:.|.:...:.
 Frog   177 ----WEILAYLILPVL---------YILIKKHIGRAHAALAEYRPILATSPVNQPRTIADKKLVF 228

  Fly   408 YLRLSVMMGVTGISEVITYFVKRHKFWRQVL----RVPNFFHLGSGIVVFVL 455
            ...:.:.:.|......|............:|    .:.|.|..|:..::|||
 Frog   229 IPIIFIFLRVWSTIRFILTLCDSPAVHNPILVTLHGIGNTFQGGANCIMFVL 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl6NP_788473.1 Mth_Ecto 25..197 CDD:119403 7/19 (37%)
7tm_4 211..398 CDD:304433 45/215 (21%)
gpr157NP_001124512.1 7tm_GPCRs 17..>192 CDD:391938 42/203 (21%)
TM helix 1 17..39 CDD:341315 7/28 (25%)
TM helix 2 48..69 CDD:341315 1/20 (5%)
TM helix 3 81..103 CDD:341315 5/21 (24%)
TM helix 4 123..139 CDD:341315 4/15 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 49 1.000 Inparanoid score I5275
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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