DRSC/TRiP Functional Genomics Resources

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Protein Alignment DNAAF19 and spag

DIOPT Version :10

Sequence 1:NP_998772.1 Gene:DNAAF19 / 388389 HGNCID:32700 Length:242 Species:Homo sapiens
Sequence 2:NP_524664.1 Gene:spag / 43958 FlyBaseID:FBgn0015544 Length:534 Species:Drosophila melanogaster


Alignment Length:226 Identity:45/226 - (19%)
Similarity:92/226 - (40%) Gaps:41/226 - (18%)


- Green bases have known domain annotations that are detailed below.


Human    11 ALEKELQAALTADEKY--KRENAAKLRAVEQRVASYEEFRGIVLASHLKP----LERKDKMGGKR 69
            |:|...:.....|.|.  :.:|.||..|.::......:     :.:.:.|    :||..::    
  Fly   331 AVETPKETETRKDTKIVPESDNEAKPSAPKKTAVEVPK-----VQTQVSPPKTTIERSPEV---- 386

Human    70 TVPWNCHTIQGRTFQDVATEISPEKAPLQ------PETSADFYRDWRRHLPSGPERYQALLQLGG 128
                  :|:|....:..::..:...:|::      |.::|.|:..|:.  .|||::||.|..:..
  Fly   387 ------NTVQTEKIEQASSNNAMSPSPIERFLPPAPTSTAQFHVTWKE--LSGPQKYQYLKSIEV 443

Human   129 PR----LGCLFQTDVGFGLLGELLVALADHVGPADRAAVLGILCSLASTGRFTLNLSLLSRAERE 189
            |.    ||..|.:|.    ..:||..:.|...|........:|..::....||:...|:|..|::
  Fly   444 PNLCKILGAGFDSDT----FADLLRTIHDFFVPNKEPNTAAVLLEISKNDEFTILAMLMSAEEKK 504

Human   190 SCKGLFQKLQ--AMGNPRSVKEGLSWEEQGL 218
            ....:...::  ...|| :|.:.| ::|.|:
  Fly   505 MVSSILNAIKNWPSKNP-AVLDNL-FKEYGV 533

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DNAAF19NP_998772.1 Dynein_attach_N 7..74 CDD:464912 11/68 (16%)
RPAP3_C 99..188 CDD:464012 24/92 (26%)
spagNP_524664.1 TPR repeat 96..124 CDD:276809
TPR 102..>211 CDD:440225
TPR repeat 129..159 CDD:276809
TPR repeat 164..192 CDD:276809
PLN03209 <296..416 CDD:178748 14/99 (14%)
RPAP3_C 416..503 CDD:464012 24/92 (26%)
Blue background indicates that the domain is not in the aligned region.

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