Protein Alignment ppk26 and scnn1b

DIOPT Version :10

• Sequence 1: NP_648125.3
• Gene: ppk26 / 38835
• FlyBaseID: FBgn0035785
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 639
• Identity: 129/639 - (20%)
• Similarity: 221/639 - (34%)
• Gaps: 179/639 - (28%)

  Fly    57 QIKYGSGFQAAKAIIHEYCDYTTIHGIRYL---GEKKRPLLERLFWISVLVLSVFTCVKLTLNIW 118
            :|:.|.|: ..|.::..:||.|..||.:.:   |.||     |:.|.      :.|.|...|..|
 Frog    19 RIQKGPGY-TYKELLVWFCDNTNTHGPKRIIKEGPKK-----RVMWF------ILTLVFAGLVFW 71

  Fly   119 DKWNNNPVIVSFAEKSTPV------WQIPFPAVTVCPETKTRREIFNFTDSYHQVRDFQSNVSGI 177
             :|  ..:|:::......|      ..:.|||||||.....:         |.:|:....::..:
 Frog    72 -QW--GVLILTYLSYGVSVSLSIGFKTMEFPAVTVCNANPYK---------YSRVKPLLKDLDAL 124

  Fly   178 V-------DLSDKQKGLYGAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSP----HFDDTYL- 230
            |       ..|.:.:......|...:....|.||.|..  .:.:||.....:|    .||:..:
 Frog   125 VATALDRIQFSSQDQANTFTQSSTNQNVTLDPTLWNHI--PLVVIDETDPSNPIVNNIFDNNAIY 187

  Fly   231 --NCKWRNSPVKCSDIFHKFVTEDGVCFSFNS-------------------LSPAEI-------- 266
              |..:|||....:....::.....:|.:.|:                   |..:.|
 Frog   188 SKNNSFRNSSEDQTSYSQRYKVAMKLCTNNNTQCVYRNFTSGIQALQEWYLLQLSSIFSNVPLAD 252

  Fly   267 -----FRAEGIIPDFIFREE----------------NRLSMDWNVE-DGYSASADTSPYPNRVLG 309
                 |:||.:|...:|..:                |....:|..| :...|||:
 Frog   253 RIAMGFKAEDLILTCLFGGQPCSYRNFTRIYDADYGNCYIFNWGQEGEDPMASAN---------- 307

  Fly   310 PGARAGLYLFMGGAEIDFDDMCRGPVQGF-------KILLHTPGDVAQVSKQYFRIPFDQEVLIS 367
            |||..||.|.:        |:.:|....:       :::||          |....||.:::.|.
 Frog   308 PGADFGLKLVL--------DIEQGEYLPYVQTTAAARLILH----------QQRSFPFVKDLGIY 354

  Fly   368 IRP----KIITTSDGLKHYEPNRRQCYFQKERELRYFNIYSQSN-------CELECLANFTLTKC 421
            ..|    .|....|.|:|.|.....|..... ::...|:|::.|       |...|.....:..|
 Frog   355 AMPGTETSIAVLVDQLEHMEAPYSSCTVNGS-DIPVQNLYAEFNSSYSIQSCLRSCYQEQMVQTC 418

  Fly   422 GCVKFSMPRNVNMPVCGDAS----LKCYNQAEDELLLREFTQGLVNAGENTRGETECNCLPSCTS 482
            ||..:..|.......|.:..    :.||....|.:..||....|              |...|..
 Frog   419 GCADYQYPLPNGSEYCSNDKYPDWVPCYYGLRDSVADRESCISL--------------CQQPCND 469

  Fly   483 IAYEAEISQADFDYK-------TVINTDSPEGKEEQSKRQGMKMSRVSIFFKEAQFLTSRRSELY 540
            ..|:..||.||:...       .|::.:..........|.|  :.|::|:|:|..:.:...||..
 Frog   470 TQYKMVISMADWPSAGAQDWIFHVLSYEKDSSHNITVNRNG--IVRLNIYFQEFNYRSITESEAT 532

  Fly   541 GTTDFLANCGGLLGLFMGVSMLSIVEL-------IYFCTVRLISNLRMRRKTRK 587
            .....|:|.||..|.:||.|:|.|:|.       ::...::|::.::.||:.|:
 Frog   533 NVVWLLSNLGGQFGFWMGGSVLCIIEFGEIIIDCVWITILKLLAWIKDRRQRRQ 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:459966	121/603 (20%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	126/630 (20%)