Protein Alignment ppk26 and Asic5

DIOPT Version :9

• Sequence 1: NP_648125.3
• Gene: ppk26 / 38835
• FlyBaseID: FBgn0035785
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_067345.1
• Gene: Asic5 / 58170
• MGIID: 1929259
• Length: 495
• Species: Mus musculus
• Alignment Length: 547
• Identity: 126/547 - (23%)
• Similarity: 205/547 - (37%)
• Gaps: 154/547 - (28%)

  Fly    68 KAIIHEYCDYTTIHGIRYLGEKKRPLLERLFWISVLVLSVFTCVKLTLNIWD---------KW-N 122
            |....::...|:.|||..:.:.:.. :.::.|::|::.||      :|.:|.         .| .
Mouse    35 KKFDQDFAMSTSFHGIHNIAQNQNK-VRKVIWLAVVLGSV------SLLVWQIYSRLVNYFTWPT 92

  Fly   123 NNPVIVSFAEKSTPVWQIPFPAVTVCPETKTRREIFNFTDSYHQVRDFQSN-VS--GIVDLSDKQ 184
            ...:.|.:.||      |.|||||:|                 .:..||:. ||  ||:..
Mouse    93 TTSIEVQYVEK------IEFPAVTLC-----------------NLNRFQTEAVSRFGIIFF---- 130

  Fly   185 KGLYGAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHF--------------DDTYLNCKWR 235
              |:..||:|.  .|.:::..|  ....|.:|.:|. ..:|              :||.::|::.
Mouse   131 --LWDIVSKVL--RLQEISANN--TGSPETLDFVTN-HQNFSITEFVKNNGFYLNNDTLVHCEFF 188

  Fly   236 NSPVKCSDIFHKFVTEDGVCFSFNSLSPAEIFRAEGIIPDFIFREENRLSMDWNVEDGYSASADT 300
            .......|..|.| ||.|.||:||        ..|.|      :.:|::|:
Mouse   189 GKTCSPKDFKHVF-TEYGNCFTFN--------YGENI------QNKNKVSV-------------- 224

  Fly   301 SPYPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPVQGFK-----ILLHTPGDVAQVSKQYFRIPF 360
                       :..||.|.:...:.:|.|   .||.||.     .::|:|....|........|.
Mouse   225 -----------SGRGLKLLLDVHQEEFTD---NPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPV 275

  Fly   361 DQEVLISIRPKIITTSDGLK--HYEPNRRQCYFQKERELRYFNIYSQSNCELECLANFTLTKCGC 423
            .....::||.        ||  |.|....:|  ....:||.|..||...|..||.|......|||
Mouse   276 GMHARVTIRQ--------LKTVHQEYPWGEC--NPNIKLRNFITYSTYGCLKECKARHIQRLCGC 330

  Fly   424 VKFSMPRNVNMPVCGDASLKC----YNQAEDELLLREFTQGLVNAGENTRGETECNCLPSCTSIA 484
            :.|.:|.|         .::|    |......:|.....:||.     |.|....:|..||....
Mouse   331 LPFLLPGN---------GVECDLLEYYNCVSPILDHIERKGLC-----TMGTHNSSCPVSCEETE 381

  Fly   485 YEAEISQADFDYKTVINTDSPEGKEEQSK---RQGMKMSRVSIFFKEAQFLTSRRSELYGTTDFL 546
            |.|.:|.:.|..:..  |.....|..||:   |:  .:..:.|.:.:..:..:::.:.....:.|
Mouse   382 YPATVSYSTFPSQRA--TRFLAKKLNQSQEYIRE--NLVNIEINYSDLNYKITQQQKAVSVPELL 442

  Fly   547 ANCGGLLGLFMGVSMLSIVELI-YFCT 572
            |:.||.||||.|.|:::|:|:| ||.|
Mouse   443 ADVGGQLGLFCGASLITIIEIIEYFFT 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:279230	122/537 (23%)
Asic5	NP_067345.1	ASC	41..466	CDD:366339	122/536 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837897
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5086
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.800