Protein Alignment ppk26 and scnn1a

DIOPT Version :10

• Sequence 1: NP_648125.3
• Gene: ppk26 / 38835
• FlyBaseID: FBgn0035785
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001184124.1
• Gene: scnn1a / 395013
• XenbaseID: XB-GENE-996083
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 612
• Identity: 130/612 - (21%)
• Similarity: 223/612 - (36%)
• Gaps: 181/612 - (29%)

  Fly    51 EVDTKKQ--IKYGSGFQAAKAIIHEYCDYTTIHGIRYLGEKKRPLLERLFWISVLVLSVFTCVKL 113
            ||..:|:  |::   |.:.:.:...:|..|||||...|...:...::..||: ||.|:.|
 Frog     4 EVKNEKEPLIEF---FSSYRELFEFFCSNTTIHGAIRLVCSRSNRMKTAFWL-VLFLATF----- 59

  Fly   114 TLNIWD------KWNNNPVIVSFAEKSTPVWQIPFPAVTVCP----------------ETKTRRE 156
            .|..|.      ::.:.||.::....|.   ::||||||||.                :.:|:|.
 Frog    60 GLMYWQFGLLFGQYFSYPVSINLNVNSD---KLPFPAVTVCTLNPYRYKAIQNDLQELDKETQRT 121

  Fly   157 IFNFTDSYHQVRDFQSNVSGIVDLSDK----QKGLYGAVSQVCEPHLHD-VTLGNKTRR-GMEII 215
            :      |...:...:.|.|.:..:.:    :.||         |||.: |..|:||.| ...:|
 Frog   122 L------YELYKYNSTGVQGWIPTNQRVRRDRPGL---------PHLLELVPPGSKTHRVSRSVI 171

  Fly   216 DALTEVSPHFDDTYLNCKWRNSPVKCS----DIFHKFVTE--DGV--CFSFNSLS-----PAEIF 267
            :...:|...        :|......|:    |.|::..|.  |.:  .:.|:.::     |.|..
 Frog   172 EEELQVKRR--------EWNIGFKLCNETGGDCFYQTYTSGVDAIREWYRFHYINILARVPEEAA 228

  Fly   268 RAEGIIPDFIFREENRLSMDWNVEDGYSASADTSPYPNRVLG--------------------PGA 312
            .....:.:|||      :..:|.|.  ...|:.|.:.:.:.|                    ||.
 Frog   229 IDGEQLENFIF------ACRFNEES--CTKANYSHFHHAIYGNCYTFNQNRSGQSNLWSSSMPGI 285

  Fly   313 RAGLYLFMGGAEIDFDDMCRGPVQGFKILLHTPGDVAQVSKQYFRIPFDQEVLISIRPKIITTSD 377
            :.||.|.:...:.|:..:. ..|.|.::|:|...:.|.:....|.||...|           ||.
 Frog   286 KNGLTLILRTEQHDYIPLL-SSVAGARVLVHGHKEPAFMDDSGFNIPPGME-----------TSI 338

  Fly   378 GLKHYEPNR-----RQC-----------YFQKERELRYFNIYSQSNCELECLANFTLTKCGCVKF 426
            |:|....||     ..|           .|:.|        |::..|...|.....:.:|||...
 Frog   339 GMKKETVNRMGGKYSDCSEDGSDVDVKNLFESE--------YTEQVCVRSCFQAAMVERCGCGYA 395

  Fly   427 SMPRNVNMPVCGDASLKCYNQAEDELLLREFTQGLVNAGENTRGETEC--NCLPSCTSIAYEA-- 487
            ..|.:.....|.....|.:.....:|:: |||       .|..|   |  .|...|....|:.
 Frog   396 FYPLSPGDEFCDYNKHKSWGHCYYKLII-EFT-------SNKLG---CFSKCRKPCLVSEYQLTA 449

  Fly   488 -------EISQADFDYKTVIN----TDSPEGKEEQSKRQGMKMSRVSIFFKEAQFLTSRRSELYG 541
                   .:|| |:.:.|:..    ||          |.|  :::::|:|:|..:.|.:.|....
 Frog   450 GYSKWPNRVSQ-DWVFHTLSRQYNLTD----------RNG--IAKLNIYFEELNYKTIQESPTIN 501

  Fly   542 TTDFLANCGGLLGLFMGVSMLSIVELI 568
            ....|:..|....|:.|.|:||:||::
 Frog   502 MVMLLSLLGSQWSLWFGSSVLSVVEML 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:459966	125/587 (21%)
scnn1a	NP_001184124.1	ENaC	18..602	CDD:273304	125/595 (21%)