DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk26 and ppk10

DIOPT Version :9

Sequence 1:	NP_648125.3	Gene:	ppk26 / 38835	FlyBaseID:	FBgn0035785	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001033894.1	Gene:	ppk10 / 3885617	FlyBaseID:	FBgn0065110	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	141/555 - (25%)
Similarity:	221/555 - (39%)	Gaps:	115/555 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 KQIKYGSGFQAAKAIIHEYCDY---TTIHGIRYLGEKKRPLLERLFWISVLVLSVFTCVKLTLNI 117
            |..||.:|.   |.:|:.:..|   ..|||.|||.:....|.|:..|:.:|:.|::.|:.:.|:.
  Fly     4 KNSKYRNGL---KIVINYFVLYFNNCCIHGFRYLTDSMLILFEKFLWLILLIASIYFCIIVCLSS 65

  Fly   118 WDKWNNNPVIVSFAEKSTPVWQIPFPAVTVCPETKTRREIFNFTDSYHQ----------VRDFQS 172
            .|::......:.. |::...|....|:|||||  ..|..|..|.|....          :.||..
  Fly    66 IDRYYTKSTHIGI-ERNYIFWNTTLPSVTVCP--VDRLNITYFADYCRNNGIKGPQRDILWDFLE 127

  Fly   173 NVSGIVDLSDKQKGLYGAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHFDDTY-LNCKWRN 236
            |::....::.:.......:.|:.|      .:|.|.....|:|..||     :|.|| .|.   |
  Fly   128 NLANSTYINFQNIPQNEQIDQIIE------DIGLKPEHYTELIYNLT-----YDRTYEPNF---N 178

  Fly   237 SPVKCSD---IFH--KFVTEDGVCFSFNSLSPAE------IFRAEGIIPDFIFREENRLSMDWNV 290
            ..::|.|   ..|  :.:||.|:|:..||....|      ||   |..|::...|...:.:.:.|
  Fly   179 ERIRCMDGAMFIHVRQVLTEWGLCYLGNSKLTEEYSSRYFIF---GKYPEYNKYEYENIRLPYQV 240

  Fly   291 EDGYSASADTSPYPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPVQGFKILLHTPGDVAQV--SK 353
              |.....||.   ..:||         |.|.|.|.|              .|:..:|.:|  :.
  Fly   241 --GSFFQKDTQ---YALLG---------FKGPAIIAF--------------AHSAFEVMKVDSNS 277

  Fly   354 QYFRIPFDQEVLISIRPKIITTSDGLKH-YEPNRRQCYFQKERELRYFNIYSQSNCELECLANFT 417
            .|   .:| .:|..:..:.||..|.|:. .....|:|.|..|..|.:|..|:::.|:.||..|..
  Fly   278 DY---AYD-GILYDLSTEEITAEDNLEQDTTVAMRRCRFPHESNLTHFPFYTRNICQQECRINLA 338

  Fly   418 LTKCGCVKFSMPRNV--NMPVCGDASLK-CY-NQAEDELLLREFTQGLVNAGENTRGETE--CNC 476
            ...|.|:....|..:  ..|||...:|: |: :.|...|.|.|         ||.:.|..  |.|
  Fly   339 YKICKCIPHFYPNRIANPKPVCDYKTLRSCFPHHASFFLKLYE---------ENGKHENPAICYC 394

  Fly   477 LPSCTSIAYEAEISQADFDYKTVINTDSPEGKEEQSKRQGMKMSRVSIFFKEAQFLTSRRSELYG 541
            ..:|               :.:|:...|........:..|...|.||:  |.......||..::.
  Fly   395 EQNC---------------HDSVVTMKSMNPMSGAKQLLGGIGSAVSV--KTWPQSRLRRQVIFS 442

  Fly   542 TTDFLANCGGLLGLFMGVSMLSIVELIYFCTVRLI 576
            .||.|.:.||..|||:|.|:|..||:|||.|:|::
  Fly   443 LTDLLVSIGGTAGLFLGFSVLGFVEVIYFFTIRIV 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:279230	131/529 (25%)
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	131/526 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920