DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk26 and ppk16

DIOPT Version :9

Sequence 1:	NP_648125.3	Gene:	ppk26 / 38835	FlyBaseID:	FBgn0035785	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	543	Identity:	134/543 - (24%)
Similarity:	212/543 - (39%)	Gaps:	107/543 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 IHEYCDYTTIHGIRYLGEKKRPLLERLFWISVLVLSVFTCVKLTLNIWDKWNNNPVIVSFAEKS- 134
            :..||..|::||..|:..:.....||.||:.|::|::.|.:.|.:..| .|:.....|:..|.|
  Fly    56 MRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLVVVSW-YWSQETPTVTVIESSH 119

  Fly   135 TPVWQIPFPAVTVCPETKTRR----------------------EIFNFTDSYHQVRDFQSNVSGI 177
            .|.|.|||||||:|...|..:                      .:||.|         ...|..:
  Fly   120 FPTWNIPFPAVTICNFNKISKSKALSLLDQMQVPVGINRSELHNLFNLT---------LLPVDTM 175

  Fly   178 VDLSDKQKGLYGAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHFDDTYLNCKWRNSPVKCS 242
            :.....||  |..:..     |:::||...|:          ::||...:...:|.|:....:|.
  Fly   176 ISNDSLQK--YDRILS-----LNNLTLNRLTQ----------QLSPDCIEMISSCIWKGINTRCE 223

  Fly   243 DIFHKFVTEDGVCFSFNSLSPAEIFRAEGIIPDFIFREENRLSMDWNVEDGYSASADTSPYPNRV 307
            .:|.:..|.:|.|.:||...        ||..:|              .:..:......||  ||
  Fly   224 SLFQRIDTMEGQCCTFNYFG--------GISNNF--------------PEKIAYQVPKRPY--RV 264

  Fly   308 LGPGARAGLYLFMGGAEID-FDDMCRGPVQGFKILLHTPGDVAQVSKQYFRIPFDQEVLISIRPK 371
            .|.|...||.:.:.....| :.....|  .||::|||...:....:.:...:...:|..:.|.|:
  Fly   265 TGCGYPTGLSVLLNPMISDYYGTFFSG--FGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPE 327

  Fly   372 IITTSDGLKHYEPNRRQCYFQKERELRYFNIYSQSNCELECLANFTLTKCGCVKFSMPRNVNMPV 436
            ....::.::..:.:.|.|.|..|..:.....||..||..||....|:..|||:...:..|.:..|
  Fly   328 STYATNDIRRMDLSLRNCLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKV 392

  Fly   437 CGDASLKCYNQAEDELLLREFTQGLVNAGENTR--GETE---CNCLPSCTSIAYEAEISQADFDY 496
            ||.....|...::     |.|:..|.|...:..  .||:   |.|||.|.|..|.:|.:....|.
  Fly   393 CGVLQTNCIIHSK-----RLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRLDI 452

  Fly   497 KTVINTDSPEGKEEQSKRQGMKMSRVSIFFKEAQFLTSRRSELYGTTDF------LANCGGLLGL 555
            ....|..:.....::        ..:.:||.:   |.|.|   |.|..|      ||:.||||||
  Fly   453 SYFANRPTFNNATDR--------ILLHVFFSD---LMSTR---YRTDIFQNWLSALASFGGLLGL 503

  Fly   556 FMGVSMLSIVELIYFCTVRLISN 578
            .||.|:::..|.|||.|.|.:.|
  Fly   504 IMGFSIVTAFEFIYFLTFRPVFN 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:279230	129/530 (24%)
ppk16	NP_001334673.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456782
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		otm24766
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	8	7.840