DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk26 and ppk18

DIOPT Version :9

Sequence 1:	NP_648125.3	Gene:	ppk26 / 38835	FlyBaseID:	FBgn0035785	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_609308.3	Gene:	ppk18 / 34295	FlyBaseID:	FBgn0265001	Length:	553	Species:	Drosophila melanogaster

Alignment Length:	556	Identity:	122/556 - (21%)
Similarity:	214/556 - (38%)	Gaps:	122/556 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 IHEYCDYTTIHGIRYLGEKKRPLLERLFWISVL-VLSVFTCVKLTLNIWDKWNNNPVIVSFAEKS 134
            :|.:..:|.   :||         .:..|::.| .:.::|.:.:. ::..::...|..:..|...
  Fly    25 LHPFLYHTP---VRY---------AKAIWLAFLTAIMIYTHIVIA-DLILEYLVQPTEIHMAPDL 76

  Fly   135 TPVWQIPFPAVTVCPETKTR-REIFNFTDS--YHQVRDFQSNVSGIVDLSDKQKGLYGAVSQVCE 196
            ..|...|||||.||...|.. |.:.::.:.  :||.......|:  :||.|....|.........
  Fly    77 VHVANSPFPAVGVCTSNKINGRLLRSYAEKLFHHQGNSSLQAVA--LDLDDMANRLLVLAQFYLN 139

  Fly   197 P--------------HLHDVTLGNKTRRGMEIIDALTEVSPHFDDTYLNCKWRNSPVKCSDIFHK 247
            |              .||.:.:......|..:.|.|.::||...|..:.......||..|.:|.|
  Fly   140 PLESDHERWNATELDRLHRLLVAYHNGAGYSVRDILRDLSPGCGDLVIRGIVFGLPVNASQLFLK 204

  Fly   248 FVTEDGVCFSFN----SLSPAEIFRAE-----GIIPDFIFREENRL-SMDWNVEDGYSASADTSP 302
            ..|...||..||    |.|.....|||     ..:|..:|...:.| |:.:.::|........:.
  Fly   205 RPTSSNVCCIFNYRRPSYSQFLTKRAEEDSEMRAVPMVVFESNSILNSVQFVLQDTPKEDITNTF 269

  Fly   303 YPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPVQGFKILLHTPGDVAQVSKQYFRIPFDQEVLIS 367
            :.|...      .|.:|              |.:.:..:..|  .:.:|...::.|     |.|.
  Fly   270 HSNSAF------QLIIF--------------PQEDYATIQST--TLGEVLVDHYSI-----VEIP 307

  Fly   368 IRPKIITTSDGLKHYEPNRRQCYFQKERELRYFN--IYSQSNCELECLANFTLTKCGCVKFSMP- 429
            |:|...::.||::...|:.|:||:.:| .:|..|  .||...|.|.|.....:..||||  |.|
  Fly   308 IQPMFFSSGDGVRGVPPHIRRCYYPEE-GMRLLNQSYYSLDECLLVCRMKSMIDHCGCV--SPPL 369

  Fly   430 --RNVNMPVCGDASLKCYNQAEDELLLR---------EFTQGLVNAGENTRGETEC-NCLPSCTS 482
              .::::..|....|.|        |:|         :|.. |.|..||. .:.:| :|||:|..
  Fly   370 TGSSMDLDYCMLPDLPC--------LMRWKSIWYGYSDFAY-LQNKEENL-VQRQCEHCLPTCNG 424

  Fly   483 IAYEAEISQADFDYKTVINTDSPEGKEEQSK------RQGMKMSR----VSIFFKEAQFLTSRRS 537
            ::            .::....:|..:...|.      .:|:...|    :.:||| .:|..:.:|
  Fly   425 VS------------MSITTNVAPLRRTYNSSGYFTGLLKGLTNERPLAIIKLFFK-LRFAQATKS 476

  Fly   538 ELYGTTDFLAN-CGGLLGLFMGVSMLSIVELIYFCT 572
            ::..:...|.| .||:|.|..|.|::|.:|::|:.|
  Fly   477 QMVSSWVVLLNRFGGILSLMYGFSIVSYIEILYYLT 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:279230	119/549 (22%)
ppk18	NP_609308.3	ASC	16..510	CDD:279230	120/552 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456779
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950