DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk26 and ppk14

DIOPT Version :9

Sequence 1:	NP_648125.3	Gene:	ppk26 / 38835	FlyBaseID:	FBgn0035785	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_609017.2	Gene:	ppk14 / 33887	FlyBaseID:	FBgn0031803	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	570	Identity:	119/570 - (20%)
Similarity:	204/570 - (35%)	Gaps:	155/570 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 VDTKKQIKYGSGFQAAKAIIHEYCDYTTIHG--IRYLGEKKRPLLERLFWISVLVLSVFTCVKLT 114
            |:||.:|:     :|...:|..|...:.|||  :.:|...:|.:  |:.|...|:.:......::
  Fly    28 VNTKSEIQ-----RAWTLLIDSYISRSHIHGLYLLFLPSMRRRM--RVLWALALICACTVLFHVS 85

  Fly   115 LNIWDKWNNNPVIVSFAEKSTPVWQIPFPAVTVC----------PETKTRREIFNFTDSYHQVRD 169
            ..:.|:::|.......|.....:..|.||.|.:|          ||.|:   ::|.|.|..::.|
  Fly    86 YLLGDRYHNKQFQTIVAHAHASIHHIAFPVVIICNKNRLNWSRLPEIKS---LYNITPSQDELFD 147

  Fly   170 FQSNVSGIVDLSDKQKGLYGAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHFDDTYLNCKW 234
               .:....|.....|  :.|...:....|.::...|.|    ||:   .::|...|:...:|.|
  Fly   148 ---RILTAYDGFSFHK--FNAFDSLLGESLDELNHLNFT----EIV---IQMSWRCDEILRDCHW 200

  Fly   235 RNSPVKCSDIFHKFVTEDGVCFSFNSLSPAEIFRAEGIIPDFIFREENRLSMDWNVEDGYSASAD 299
            :.:...|..:|.......|.|.:||.|                  |:.|             ..:
  Fly   201 QTASRDCCKLFRPRRLPLGYCLAFNEL------------------EKRR-------------GTE 234

  Fly   300 TSPYPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPVQGFKILL----HTPGD--------VAQVS 352
            |          |...||.|                    ::||    |.||:        ....|
  Fly   235 T----------GINTGLLL--------------------RLLLREGQHAPGNSGLKGFWLTVVES 269

  Fly   353 KQYFRIPFDQEVLISIRPKIITTSDGLKHY--------EPNRRQCYFQKERELRYFNI-----YS 404
            ..:|..|.  ||:...|..:..|:  :.||        ..:.|.|....|.|..:|..     |.
  Fly   270 SVWFGFPI--EVVPHSRTNVAVTA--VYHYFDESTLSLPSSWRHCVMDYEEESEHFRTLEGQKYM 330

  Fly   405 QSNCELECLANFTLTKCGC-VKFSMPRNVNMPVCGDASLKCYNQAEDELLLREFTQGLVNAGENT 468
            ..||:.||...:.|..|.| |....|.: |.|.|....|.|.  |....||:.|.|    .||:.
  Fly   331 LENCQAECQQRYLLRYCNCTVDLFYPPS-NYPACRLKDLPCL--AAHNHLLQNFEQ----PGEHP 388

  Fly   469 RGETE-----CNCLPSCTSIAYEAEISQADFDYKTVINTDSPEGKEE---QSKRQGMKMSRVSIF 525
            ....|     |.||.:|.|:               .:.||..:..::   |.....::...::::
  Fly   389 YVHREESGLVCECLHNCKSL---------------TLLTDMRKSVQQPWLQPNSSAIESMWLNVY 438

  Fly   526 FKEAQFLTSRRSELYGTTDFLANCGGLLGLFMGVSMLSIVELIYFCTVRL 575
            ||:...|..:.:.:|...|.:.:.||:..|.:|.|::|::|.::|...::
  Fly   439 FKKPSMLVYKTNLIYTWVDLIVSFGGICQLCLGCSIISLIEFVFFALYKV 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:279230	112/541 (21%)
ppk14	NP_609017.2	ASC	45..483	CDD:279230	112/541 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14782
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020