Protein Alignment ppk26 and asic-2

DIOPT Version :10

• Sequence 1: NP_648125.3
• Gene: ppk26 / 38835
• FlyBaseID: FBgn0035785
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_492099.1
• Gene: asic-2 / 189058
• WormBaseID: WBGene00012137
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 122/545 - (22%)
• Similarity: 201/545 - (36%)
• Gaps: 114/545 - (20%)

  Fly    61 GSGFQAAKAIIHEYCDYTTIHGIRYLGEKKRPLLERLFWISV--LVLSVFTCVKLTLNIWDKWNN 123
            |.||   ..|..::.:::|:..:.::...... :.|:|||::  .||.:| ..:|.:.| .|:.:
 Worm     3 GGGF---VQIFKDFSNWSTVAVVPHVANANNK-ISRIFWIAIFLFVLGMF-AYELYILI-AKFFS 61

  Fly   124 NPVIVS---FAEKSTPVWQIPFPAVTVCPETKTRREIFNFTDSYHQVRDFQSNVSG--IVDLSDK 183
            .|..|:   ..||     || ||.||||.....:..:.....::..|....:..|.  :...|..
 Worm    62 YPATVNTEILFEK-----QI-FPVVTVCNMNPYKYSVVKSNSAFSSVNTLMTTYSDATVGTFSTD 120

  Fly   184 QKGLYG-------AVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHFDDTYLNCKWRNSPVKC 241
            :.|||.       ..|:..:..:.:..|.:.|.:    :.||..    :.|...:|.:...|...
 Worm   121 KWGLYADNDETYDLDSRAADALVLEANLISDTAK----VPALYT----YADLIQDCSFAGIPCSE 177

  Fly   242 SDIFHKFVTE-DGVCFSFN---SLSPAEIFRAEGIIPDFIFREENRLSMDWNVEDGYSASADTSP 302
            || |.||:.. .|.|:|||   ||:.:  ...|||    .|..:..|::.....:|     :|..
 Worm   178 SD-FTKFIDPVYGACYSFNEDASLNYS--VSREGI----QFGLKLMLTVTQTKTNG-----NTDS 230

  Fly   303 YPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPVQGFKILLHTPGDVAQVSKQYFRIPFDQEVLIS 367
            .|...|. |||.|:             ..||...|    |.:.|..|.|.       ::..|.:|
 Worm   231 LPTTKLA-GARIGV-------------NSRGSSPG----LDSNGIDAGVG-------YESAVSVS 270

  Fly   368 IRPKIITTSDGLKHY------EPNRRQCYFQKERELRYFNIYSQSNCELECLANFTLTKCGCVKF 426
            :...:    ...|.|      ||:....|       :.| ||:...|...|....|:.||.|..
 Worm   271 LTQNV----RAKKPYGTCVDREPDSSDYY-------KDF-IYTLETCFNGCKQRDTIAKCQCAN- 322

  Fly   427 SMPRNVNMPVCGDASLKCYNQAEDELLLREFTQGLVNAGENTRGETECNCLPSCTSIAYEAEISQ 491
              ||    ...|.....|.....|...|:.......::..|.....||||.|.|....|...:|.
 Worm   323 --PR----LALGSTDTACQPIKADLDCLQTLKGNQTSSTPNIDLLVECNCNPPCDESTYTPTVSL 381

  Fly   492 ADFDYKT-VINTDSPEGKEEQSKRQGMKMSR-------------VSIFFKEAQFLTSRRSELYGT 542
            |.|...: .:.|.|..|....|.......|:             :.:|.:...:.....:..|..
 Worm   382 AQFPSTSYYVATSSTAGVGSCSSTNSKFSSKSDCQKWYNNNGMIIQVFLETLSYELYTETAGYTV 446

  Fly   543 TDFLANCGGLLGLFMGVSMLSIVEL 567
            ::.:.:.||..||::|:|::|:||:
 Worm   447 SNVINDLGGQAGLWLGLSVISVVEM 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:459966	118/532 (22%)
asic-2	NP_492099.1	deg-1	12..474	CDD:273309	118/533 (22%)