Protein Alignment ppk26 and mec-4

DIOPT Version :9

• Sequence 1: NP_648125.3
• Gene: ppk26 / 38835
• FlyBaseID: FBgn0035785
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_510712.2
• Gene: mec-4 / 181728
• WormBaseID: WBGene00003168
• Length: 768
• Species: Caenorhabditis elegans
• Alignment Length: 737
• Identity: 135/737 - (18%)
• Similarity: 225/737 - (30%)
• Gaps: 275/737 - (37%)

  Fly    73 EYCDYTTIHGIRYLGEKKRPLLERLFWISVLVLSVFTCVKLTLN---IWDKWNNNPVIVSFAEKS 134
            |:|..|:.|||..:||... :..|..|:   ||.:...:.|.||   :.||:|.|..||....|.
 Worm    86 EFCYKTSAHGIPMIGEAPN-VYYRAVWV---VLFLGCMIMLYLNAQSVLDKYNRNEKIVDIQLKF 146

  Fly   135 TPVWQIPFPAVTVC--------------------------------------------------- 148
            ...   ||||:|:|
 Worm   147 DTA---PFPAITLCNLNPYKASLATSVDLVKRTLSAFDGAMGKAGGNKDHEEEREVVTEPPTTPA 208

  Fly   149 PETK----------------------------------------------TRREIFNFTDSYHQV 167
            |.||                                              |.:::||..|
 Worm   209 PTTKPARRRGKRDLSGAFFEPGFARCLCGSQGSSEQEDKDEEKEEELLETTTKKVFNIND----- 268

  Fly   168 RDFQSNVSGIVDLSDKQKGLYGAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHFDD----- 227
                         :|::   :..:.:....|..:..:...|  ||.:::........||:
 Worm   269 -------------ADEE---WDGMEEYDNEHYENYDVEATT--GMNMMEECQSERTKFDEPTGFD 315

  Fly   228 ----------------TYLNCKWRNSPV-KCSDIFHKFVTEDG----------------VCFSFN 259
                            .:||..|..:.. .|::  |.|.|:|.                .|.::|
 Worm   316 DRCICAFDRSTHDAWPCFLNGTWETTECDTCNE--HAFCTKDNKTAKGHRSPCICAPSRFCVAYN 378

  Fly   260 SLS-PAEIFR-AEGII----PDFI------------------------------FREENRLSMD- 287
            ..: |.||:. .:|..    |:|:                              .::..|||..
 Worm   379 GKTPPIEIWTYLQGGTPTEDPNFLEAMGFQGMTDEVAIVTKAKENIMFAMATLSMQDRERLSTTK 443

  Fly   288 -------------WNVEDGYSASADTSPYPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPVQGFK 339
                         .::|..:....|.           |....:.|.....::...:..||:.|.:
 Worm   444 RELVHKCSFNGKACDIEADFLTHIDP-----------AFGSCFTFNHNRTVNLTSIRAGPMYGLR 497

  Fly   340 ILLH---------TPGDVAQVS---KQYFRIPFDQEVLISIRPKIITTSDGLKHYEPNRRQCYF- 391
            :|::         |.....:::   |:.|  ||......| .|....:|.||:..:.:|....:
 Worm   498 MLVYVNASDYMPTTEATGVRLTIHDKEDF--PFPDTFGYS-APTGYVSSFGLRLRKMSRLPAPYG 559

  Fly   392 -----QKERELRYFNI-YSQSNCELECLANFTLTKCGC--VKFSMPRNVNMPVCGD-ASLKCYNQ 447
                 .|..:..|.|. ||...|...|.....|.:|.|  .:|.:|.|.......| .:.||.:.
 Worm   560 DCVPDGKTSDYIYSNYEYSVEGCYRSCFQQLVLKECRCGDPRFPVPENARHCDAADPIARKCLDA 624

  Fly   448 AEDELLLREFTQGLVNAGENTRGETECNCLPSCTSIAYEAEISQADFDYKTV-INTDSPEGKE-E 510
            ..::|      .||       .|...|.|...|....|....|.|.:...:: |...|..|.. |
 Worm   625 RMNDL------GGL-------HGSFRCRCQQPCRQSIYSVTYSPAKWPSLSLQIQLGSCNGTAVE 676

  Fly   511 QSKRQGMKMSRVSIFFKEAQFLTSRRSELYGTTDFLANCGGLLGLFMGVSMLSIVELIY-FCTVR 574
            .:|......:.|.:|:::..|.....||.||..:.||:.||.|||:.|:|.|:..|.:: |....
 Worm   677 CNKHYKENGAMVEVFYEQLNFEMLTESEAYGFVNLLADFGGQLGLWCGISFLTCCEFVFLFLETA 741

  Fly   575 LIS---NLRMRRKTRKELLKAV 593
            .:|   |..:.:|.:.|..|.:
 Worm   742 YMSAEHNYSLYKKKKAEKAKKI 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:279230	128/708 (18%)
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	129/708 (18%)
		ASC	87..>172	CDD:279230	27/91 (30%)
		ASC	<428..739	CDD:295594	72/337 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820