Protein Alignment ppk26 and Asic3

DIOPT Version :9

• Sequence 1: NP_648125.3
• Gene: ppk26 / 38835
• FlyBaseID: FBgn0035785
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 606
• Identity: 126/606 - (20%)
• Similarity: 202/606 - (33%)
• Gaps: 170/606 - (28%)

  Fly    58 IKYGSGFQAAK----AIIHEYCDYTTIHGIRYLGEKKRPLLERLFWISVLVLSVFTCVKLTLNIW 118
            :|..||.:.|:    :.|..:.:..|:||:.::.......|.|..|.:.::||      |...::
Mouse     1 MKPPSGLEEAQRRQASDIRVFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLS------LAAFLY 59

  Fly   119 DKWNNNPVIVSFAEKST----PVWQIPFPAVTVCPETKTRREIFNFTDSYHQVRDFQSNVSGIVD 179
            ...........|..|:|    ...|:.|||||:|.....||       |.....|.....:.::.
Mouse    60 QVAERVRYYGEFHHKTTLDERESHQLTFPAVTLCNINPLRR-------SRLTPNDLHWAGTALLG 117

  Fly   180 LSDKQKGLY-GAVSQVCEPHLHDVTLGNKTRRGMEIIDALTEVSPHFDDTYLNCKWRNSPVKCS- 242
            |...:...| .|:.|...|.      |.......::...........:|..|:|::|..|  |.
Mouse   118 LDPAEHAAYLRALGQPPAPP------GFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQP--CGP 174

  Fly   243 DIFHKFVTEDGVCFSFNSLSPAEIFRAEGIIPDFIFREENRLSMDWNVEDGYSASADTSPYPNRV 307
            :.|....|..|.|::|||       .|:|                        |...|:|
Mouse   175 ENFTVIFTRMGQCYTFNS-------GAQG------------------------AELLTTP----- 203

  Fly   308 LGPGARAGLYLFMGGAEIDF----DDMCRGPVQ-GFKILLH---------------TPGDVAQVS 352
             ..||..||.:.:...:.::    .||...|.: |.::.:|               .||....||
Mouse   204 -KGGAGNGLEIMLDVQQEEYLPIWKDMEETPFEVGIRVQIHGQEEPPAIDQLGFGAAPGHQTFVS 267

  Fly   353 KQYFRI-----PFDQEVLISIRPKI-ITTSD--GLKHYEPNRRQCYFQKERELRYFNIYSQSNCE 409
            .|..::     |:......|:.|.. ...||  |.....|.                 ||...|.
Mouse   268 CQQQQLSFLPPPWGDCNTASVDPDFDPEPSDPLGSPSSSPP-----------------YSLIGCR 315

  Fly   410 LECLANFTLTKCGCVKFSMPRNVNMPVCGDASLK-C----------------------YNQAEDE 451
            |.|.:.:...||||....||.  |.|||.....| |                      :|.....
Mouse   316 LACESRYVARKCGCRMMHMPG--NSPVCSPQQYKDCASPALGKAHLFSLPVPIHSDIDHNPLGQV 378

  Fly   452 LLLREFTQGLVNAGENTRGETECNCLPSCTSIAYEAEISQADFDYKTVINTDSPEGKEEQSKRQG 516
            ||.    ..|..|....|.:| |.|...|.:..|..|:|......:.            .::...
Mouse   379 LLF----LALRPADAMLRKDT-CVCPNPCATTRYAKELSMVRIPSRA------------SARYLA 426

  Fly   517 MKMSR-----------VSIFFKEAQFLTSRRSELYGTTDFLANCGGLLGLFMGVSMLSIVELI-Y 569
            .|.:|           :.|||:...:....:...|..::.|.:.||.:|||:|.|:|:|:|:: |
Mouse   427 RKYNRSETYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDY 491

  Fly   570 FCTV---RLISNLRMRRKTRK 587
            .|.|   |::.....||.:::
Mouse   492 LCEVFQDRVLGYFWNRRSSQR 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:279230	115/564 (20%)
Asic3	XP_006535700.1	ASC	21..546	CDD:383197	121/586 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920