Protein Alignment ppk26 and asic1

DIOPT Version :10

• Sequence 1: NP_648125.3
• Gene: ppk26 / 38835
• FlyBaseID: FBgn0035785
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_004912018.1
• Gene: asic1 / 100489966
• XenbaseID: XB-GENE-977699
• Length: 525
• Species: Xenopus tropicalis
• Alignment Length: 552
• Identity: 120/552 - (21%)
• Similarity: 207/552 - (37%)
• Gaps: 138/552 - (25%)

  Fly    52 VDTKKQIKYGSGFQAAKAIIHEYCDYTTIHGIRYLGEKKRPLLERLFWI----SVLVLSVFTCVK 112
            :|.|:..:.||   .....:..:...:|:||:.::...:|....||.|:    ..|.|.::.|.:
 Frog     1 MDVKEAEELGS---PQPLSVQAFASGSTLHGLAHIFTYERFSCRRLIWVLCFLGSLSLLLYVCTE 62

  Fly   113 LTLNIWDKWNNNPVIVSFAEKSTPVWQIPFPAVTVCPETKTRREIFNFTDSYHQVRDFQSNVSGI 177
            ..:..::    .|.:....|.|||  ::.|||||.|...:.|.......|.|| ..:..|.::..
 Frog    63 RIIYYFE----YPHVTKLDEISTP--RMIFPAVTFCNLNEFRFSRVTKNDLYH-AGELLSLLNNR 120

  Fly   178 VDLSDKQKGLYGAVSQVCEPHLHDVTLGNKT-----------------RRGMEIIDALTEVSPHF 225
            .:|.|         ||:.:..:.:: |.:|.                 |.|.:|.:.|
 Frog   121 YELPD---------SQLADEKVMEI-LQDKANFRNFKPKPFNMREFYDRTGHDIREML------- 168

  Fly   226 DDTYLNCKWRNSPVKCS-DIFHKFVTEDGVCFSFNSLSPAEIFRAEGIIPDFIFREENRLSMDWN 289
                |:||:|..  :|| |.|....|..|.|::|||
 Frog   169 ----LSCKYRGE--ECSVDDFVPVFTRYGKCYTFNS----------------------------- 198

  Fly   290 VEDGYSASADTSPYPNRVLGPGARAGLYLFMGGAEIDFDDMCRGPV----------QGFKILLHT 344
            ..:|.|....|.        .|...||.|.:   :|..|:..  ||          .|.|:.:|:
 Frog   199 GRNGRSPLVTTK--------GGTGNGLELML---DIQQDEYL--PVWGETDETSFEAGIKVQIHS 250

  Fly   345 PGDVAQVSKQYFRIPFDQEVLISIRPKIITTSDGLKHYEPNRRQCYFQKERELRYFNIYSQSNCE 409
            ..:...:.:..|.:....:..:|.:.:.:|      :..|....|. ....:..:|:.||.|.|.
 Frog   251 QDEPPFIDQLGFGVAPGFQTFVSCQEQRLT------YLPPPWGDCK-SSAMDSEFFDTYSISACR 308

  Fly   410 LECLANFTLTKCGCVKFSMPRNVNMPVCGDASL---KCYNQAEDELLLREFTQGLVNAGENTRGE 471
            ::|...:.:..|.|      |.|:||  |||:.   :.|.:..|..|  :|   ||.     :..
 Frog   309 IDCETRYLVENCNC------RMVHMP--GDAAYCTPELYKECADPAL--DF---LVE-----KDN 355

  Fly   472 TECNCLPSCTSIAYEAEISQADFDYKTVINTDSPE-GKEEQSKRQGMKMSRVSIFFKEAQFLTSR 535
            ..|.|...|....|..|:|......|......:.: .|.||...:.:.:  :.|||:...:.|..
 Frog   356 DFCVCETPCNMTRYGKELSMVKIPSKASARYLAKKYNKSEQYIAENILV--LDIFFEALNYETIE 418

  Fly   536 RSELYGTTDFLANCGGLLGLFMGVSMLSIVEL 567
            :.:.|.....|.:.||.:|||:|.|:|:::||
 Frog   419 QKKAYEVAGLLGDIGGQMGLFIGASILTVLEL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk26	NP_648125.3	ASC	74..570	CDD:459966	116/530 (22%)
asic1	XP_004912018.1	ENaC	18..507	CDD:273304	116/532 (22%)