DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sphinx2 and CG3505

DIOPT Version :9

Sequence 1:	NP_001303408.1	Gene:	sphinx2 / 38833	FlyBaseID:	FBgn0052382	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	53/257 - (20%)
Similarity:	97/257 - (37%)	Gaps:	72/257 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 YLVGIVYAKSPLSSLKFGAGTIISNQWILTVKEVLIFKYIEAHFGSKRAFWGYDILRI------- 96
            :|..|.|.:.....:....|.:||::::||.          ||..::.|.....|..:
  Fly   120 WLALIEYTRGNQEKIHACGGVLISDRYVLTA----------AHCVAQAATSNLQITAVRLGEWDT 174

  Fly    97 -------YREN----------------------FYFHYDKTRI--IALVK-CPYQKFDRRMSRVR 129
                   |.|:                      .|...|:|:|  ||||: ....|.:..:..:.
  Fly   175 STNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPIC 239

  Fly   130 VPAYGARFERYVGNMTMVCGW--GTDKRKVRLPTWMRCVEVEVMNNTEC----AKYHTPLKWYEM 188
            :|....|.:.....:|.|.||  .:.:|       ||...|.:.:..||    |.....::..::
  Fly   240 LPNKQLRADELEDLVTEVAGWQASSSQR-------MRKGYVTISSIEECQRKYASQQLRIQASKL 297

  Fly   189 C--TSGEGFKGVCEGDMGGAVVTMGPNPTFI--GIIWLMPTNC-SIGYPSVHIRVSDHIKWI 245
            |  |:.:    .|.|:.||.:: :..|..::  |::...|..| :..:|.|:.||:.:|.||
  Fly   298 CGLTNSQ----ECYGNAGGPLM-LFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWI 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sphinx2	NP_001303408.1	Tryp_SPc	25..245	CDD:214473	51/255 (20%)
sphinx2	NP_001303408.1	Tryp_SPc	26..248	CDD:304450	53/257 (21%)
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	53/257 (21%)
		Tryp_SPc	111..354	CDD:214473	51/255 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030