DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac2 and RHO3

DIOPT Version :9

Sequence 1:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_012148.1	Gene:	RHO3 / 854688	SGDID:	S000001380	Length:	231	Species:	Saccharomyces cerevisiae

Alignment Length:	219	Identity:	90/219 - (41%)
Similarity:	121/219 - (55%)	Gaps:	36/219 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLRP 69
            |.|::||||.|||.||..:|...||..|.||||:||..::.||:|.|.|.||||||||::||||.
Yeast    18 KIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDTAGQEEFDRLRS 82

  Fly    70 LSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKKL 134
            |||..|...::|||:.:..|.|||:.||..|:..||..|.::||..|.|||:::.     :...:
Yeast    83 LSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNEN-----ESNAI 142

  Fly   135 TP--------------------------ITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAI 173
            ||                          |:|.:||||||:|.|::||||||...||:...|.||.
Yeast   143 TPNNIQQDNSVSNDNGNNINSTSNGKNLISYEEGLAMAKKIGALRYLECSAKLNKGVNEAFTEAA 207

  Fly   174 RSVLC--PV---VRGPKRHKCALL 192
            |..|.  ||   |:......|.::
Yeast   208 RVALTAGPVATEVKSDSGSSCTIM 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	85/196 (43%)
RHO3	NP_012148.1	Rho3	17..231	CDD:206706	90/217 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810