DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac2 and CDC42

DIOPT Version :9

Sequence 1:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_013330.1	Gene:	CDC42 / 850930	SGDID:	S000004219	Length:	191	Species:	Saccharomyces cerevisiae

Alignment Length:	193	Identity:	132/193 - (68%)
Similarity:	160/193 - (82%)	Gaps:	3/193 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYD 65
            ||.:||||||||||||||||||||||.||.:|:|||||||:..||:..:|..|||:|||||||||
Yeast     1 MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYD 65

  Fly    66 RLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLK 130
            ||||||||.|||||:|||:::|.|||||:.||||||.||||.||.::|||::||||||..||||:
Yeast    66 RLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQ 130

  Fly   131 DKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVL-CPVVRGPKRHKCALL 192
            .::|.|||..||..:|:|:.||||:|||||||:|||.||||||.:.| .||::  |..|||:|
Yeast   131 RQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIK--KSKKCAIL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	122/172 (71%)
CDC42	NP_013330.1	Cdc42	3..177	CDD:206664	122/173 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000070
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X103
TreeFam	0	0.000	Not matched by this tool.
	4	3.810