DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac2 and rhobtb2a

DIOPT Version :9

Sequence 1:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	XP_001332198.5	Gene:	rhobtb2a / 792631	ZFINID:	ZDB-GENE-081105-67	Length:	543	Species:	Danio rerio

Alignment Length:	210	Identity:	82/210 - (39%)
Similarity:	118/210 - (56%)	Gaps:	31/210 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNY--------SANVMVDAK 49
            ::.||||||||.|||||.|:.:...||...:|      :|||:  |.|        .:..:||..
Zfish    36 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDV 100

  Fly    50 PINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVG 114
            .::|.||||.|  |:.:.|..:|.::||.::|||:.||.|..:||..|:||::|.||..|:||||
Zfish   101 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVRTMWYPEIKHFCPRAPVILVG 163

  Fly   115 TKLDLR-DDKQTIEKLKDKKLTPITYPQGLA------MAKEIAAVKYLECSALTQKGLKTVFDEA 172
            .:|||| .|.:.:.:.:.....||...:.||      :|||: .|.|.|.|.:.|.|:|.|||.|
Zfish   164 CQLDLRYADLEAVNRARRPLARPIKSNEILAPEKGREVAKEL-GVPYYETSIVAQFGVKDVFDNA 227

  Fly   173 IRSVLCPVVRGPKRH 187
            ||:.|.     .:||
Zfish   228 IRAALI-----SRRH 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	79/195 (41%)
rhobtb2a	XP_001332198.5	RhoBTB	37..231	CDD:133275	79/196 (40%)
		RHO	41..232	CDD:197554	77/193 (40%)
		BTB	283..>321	CDD:295341
		BTB	<407..468	CDD:295341
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910