DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac2 and RHOF

DIOPT Version :9

Sequence 1:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_061907.2	Gene:	RHOF / 54509	HGNCID:	15703	Length:	211	Species:	Homo sapiens

Alignment Length:	192	Identity:	97/192 - (50%)
Similarity:	131/192 - (68%)	Gaps:	3/192 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRLR 68
            :|.|:||||..|||.||:.|:..:||..|.|:||:.|:|:|.|.:|.:.|.|:||||||||||||
Human    20 LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDYDRLR 84

  Fly    69 PLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLKDKK 133
            ||||..|.:.|||:.::||.|::||..||||||.|.|..:|::|:|.|.|||.||:.:.||:..:
Human    85 PLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQ 149

  Fly   134 LTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIR---SVLCPVVRGPKRHKCALL 192
            |.||||.|||:..::|.|..||||||..::.::.||.||.:   |.|....|..||..|.||
Human   150 LEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQRQKKRRLCLLL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	89/174 (51%)
RHOF	NP_061907.2	Rho4_like	17..211	CDD:206704	95/190 (50%)
		RHO	22..195	CDD:197554	88/172 (51%)
		Effector region. /evidence=ECO:0000255	48..56		4/7 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820