DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac2 and Rhobtb2

DIOPT Version :9

Sequence 1:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001013151.1	Gene:	Rhobtb2 / 306004	RGDID:	1309924	Length:	728	Species:	Rattus norvegicus

Alignment Length:	213	Identity:	80/213 - (37%)
Similarity:	120/213 - (56%)	Gaps:	37/213 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNY--------SANVMVDAK 49
            ::.||||||||.|||||.|:.:...||...:|      :|||:  |.|        .:..:||..
  Rat    12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDV 76

  Fly    50 PINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVG 114
            .::|.||||.|  |:.:.|..:|.::||.::|||:.||.|..:|:..|:||::|.||..|:||||
  Rat    77 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVG 139

  Fly   115 TKLDLR-DDKQTIEK--------LKDKKLTPITYPQ-GLAMAKEIAAVKYLECSALTQKGLKTVF 169
            .:|||| .|.:.:.:        :|..::.|   |: |..:|||: .:.|.|.|.:.|.|:|.||
  Rat   140 CQLDLRYADLEAVNRARRPLARPIKPNEILP---PEKGREVAKEL-GIPYYETSVVAQFGIKDVF 200

  Fly   170 DEAIRSVLCPVVRGPKRH 187
            |.|||:.|.     .:||
  Rat   201 DNAIRAALI-----SRRH 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	77/198 (39%)
Rhobtb2	NP_001013151.1	RhoBTB	13..207	CDD:133275	77/199 (39%)
		BTB_POZ	250..475	CDD:365784
		BTB2_POZ_RHOBTB2	480..603	CDD:349668
		BACK_RHOBTB2	608..704	CDD:350606
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810