DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac2 and Rhoh

DIOPT Version :9

Sequence 1:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001013448.1	Gene:	Rhoh / 305341	RGDID:	1307623	Length:	191	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	77/186 - (41%)
Similarity:	120/186 - (64%)	Gaps:	7/186 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYD 65
            :.:||||:|||.|||||.||:.:|:..||..|.|||::|...:|.:|...|:||||||||.:.:.
  Rat     2 LSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFR 66

  Fly    66 RLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLK 130
            .:|||||.|.||.|:|:|:.|.:||.|::.||..|||.:.|..|:::|.|:.|.|:       :.
  Rat    67 SIRPLSYQQADVVLMCYSVANHSSFLNLKNKWISEVRSNLPCTPVLVVATQTDQRE-------MG 124

  Fly   131 DKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKR 186
            ..:.:.|...:|..:|:::.|..|||||||:.:|::.||:.|:|:.:....|..:|
  Rat   125 PHRASCINAIEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	75/172 (44%)
Rhoh	NP_001013448.1	Rho	5..169	CDD:206641	74/170 (44%)
Rhoh	NP_001013448.1	RHO	7..173	CDD:197554	73/172 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24072
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920