DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac2 and rhobtb1

DIOPT Version :9

Sequence 1:	NP_001261517.1	Gene:	Rac2 / 38831	FlyBaseID:	FBgn0014011	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	XP_003199615.1	Gene:	rhobtb1 / 100537290	ZFINID:	ZDB-GENE-130530-871	Length:	687	Species:	Danio rerio

Alignment Length:	214	Identity:	76/214 - (35%)
Similarity:	115/214 - (53%)	Gaps:	39/214 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNY--------SANVMVDAK 49
            ::.||||||||.|||||.|:.:...|....:|      :|||:  |.|        .:..:||..
Zfish     8 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDV 72

  Fly    50 PINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVG 114
            .::|.||||.|  |:.:.|..:|.::||.::|||:.||.|..:|:..|:.|::|.||..|:||||
Zfish    73 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYLEIKHFCPRTPVILVG 135

  Fly   115 TKLDLR-DDKQTIEKLKDKKLTPITYP----------QGLAMAKEIAAVKYLECSALTQKGLKTV 168
            .:|||| .|.:.:.:.:    .|::.|          .|..:|||: .:.|.|.|...|.|:|.:
Zfish   136 CQLDLRYADLEAVNRAR----RPLSRPIKPGDILPPESGREVAKEL-GIPYYETSVFDQFGIKDI 195

  Fly   169 FDEAIRSVLCPVVRGPKRH 187
            ||.|||:.|.     .:||
Zfish   196 FDNAIRAALI-----SRRH 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac2	NP_001261517.1	Rac1_like	3..176	CDD:206663	73/199 (37%)
rhobtb1	XP_003199615.1	RhoBTB	9..203	CDD:133275	73/200 (37%)
		BTB	355..446	CDD:333434
		BTB	477..569	CDD:197585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810