DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8560 and AGBL2

DIOPT Version :9

Sequence 1:NP_001261516.1 Gene:CG8560 / 38830 FlyBaseID:FBgn0035781 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_079059.2 Gene:AGBL2 / 79841 HGNCID:26296 Length:902 Species:Homo sapiens


Alignment Length:307 Identity:62/307 - (20%)
Similarity:99/307 - (32%) Gaps:111/307 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 HRHAEINAYLDELA--AAYPSRVSVQVAGKSYENRDIKTITITN----GDGKTGKNVVFLDAGIH 182
            :.:.::..||..:|  ........:|...:|.....:..:||||    ......|..|.|.|.:|
Human   398 YTYTDLQCYLLSVANNPIQSQFCKLQTLCRSLAGNTVYLLTITNPSQTPQEAAAKKAVVLSARVH 462

  Fly   183 AREWIAHAGALYVIHQLVENFAANS---ELLKD-FDWVILPVVNPDG-----YEYSHTTTRMWRK 238
            ..|    :...:|:...::...:||   :||:| |.:.:||::||||     |..|         
Human   463 PGE----SNGSWVMKGFLDFILSNSPDAQLLRDIFVFKVLPMLNPDGVIVGNYRCS--------- 514

  Fly   239 TRKPISSACYGTDANRNFDFHWGEVGASSYSC----SDTFKGETAFSEPETQLI--RDILLSLTG 297
                    ..|.|.||    |:..:...|:.|    .:..|          :|:  |::||    
Human   515 --------LAGRDLNR----HYKTILKESFPCIWYTRNMIK----------RLLEEREVLL---- 553

  Fly   298 RGKFYLTLHSY---GNYLLYPWGWTSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYA 359
                |...|.:   .|..||          ...:|:.               ||.:......|..
Human   554 ----YCDFHGHSRKNNIFLY----------GCNNNNR---------------KYWLHERVFPLML 589

  Fly   360 AAGGSDDYAFGVANFPV-------------------SITMELPAGGT 387
            .....|.::|...||.|                   |.|||...||:
Human   590 CKNAPDKFSFHSCNFKVQKCKEGTGRVVMWRMGILNSYTMESTFGGS 636

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8560NP_001261516.1 Propep_M14 29..98 CDD:280416
M14_CP_A-B_like 123..414 CDD:199844 62/307 (20%)
AGBL2NP_079059.2 GVQW 105..>120 CDD:290611
M14_AGBL2-3_like 407..666 CDD:133117 61/298 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 746..770
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 796..879
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2866
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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