DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8560 and Agtpbp1

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001364026.1	Gene:	Agtpbp1 / 67269	MGIID:	2159437	Length:	1218	Species:	Mus musculus

Alignment Length:	310	Identity:	54/310 - (17%)
Similarity:	101/310 - (32%)	Gaps:	115/310 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VALAVENYDGYKIYDINARNAFEKQLLLRLSG---NEAYDF--------------------FDLP 55
            :.:....||.....|||: |.:.:.....:||   ..||.|                    :.:.
Mouse   717 IQIRKSEYDLILNSDINS-NHYHQWFYFEVSGMRPGVAYRFNIINCEKSNSQFNYGMQPLMYSVQ 780

  Fly    56 RSLDAS-----------------SRVMVKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDEN 103
            .:|:|.                 ||..|....|:|..:    |.:.::|   ||     ..:|:
Mouse   781 EALNARPWWIRMGTDICYYKNHFSRSSVAAGGQKGKSY----YTITFTV---NF-----PHKDD- 832

  Fly   104 QNQRLMNLRSAERSVSFKAFH---RHAEINAYLDELAAAY-PSRVSVQVAGKSYENRDI------ 158
                          |.:.|:|   .::.:..:|.:|.:|: |.::        |..:|:
Mouse   833 --------------VCYFAYHYPYTYSTLQMHLQKLESAHNPQQI--------YFRKDVLCETLS 875

  Fly   159 ----KTITITNGDGKT---------GKNVVFLDAGIHARE----WIAHAGALYVIHQLVENFAAN 206
                ..:|||......         .:..:||.|.:|..|    |:...    .:..|:.|....
Mouse   876 GNICPLVTITAMPESNYYEHICQFRTRPYIFLSARVHPGETNASWVMKG----TLEYLMSNSPTA 936

  Fly   207 SELLKDFDWVILPVVNPDG-YEYSHTTT-------RMWRKTRKPISSACY 248
            ..|.:.:.:.|:|::|||| ...:|..:       |.|:.....:....|
Mouse   937 QSLRESYIFKIVPMLNPDGVINGNHRCSLSGEDLNRQWQSPNPELHPTIY 986

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	19/108 (18%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	29/161 (18%)
Agtpbp1	NP_001364026.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	476..512
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	590..617
		Pepdidase_M14_N	704..838	CDD:407865	24/148 (16%)
		M14_Nna1	861..1131	CDD:349477	24/138 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1193..1218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900