Protein Alignment CG8560 and CPA6

DIOPT Version :10

• Sequence 1: NP_648120.3
• Gene: CG8560 / 38830
• FlyBaseID: FBgn0035781
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_065094.3
• Gene: CPA6 / 57094
• HGNCID: 17245
• Length: 437
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 119/432 - (27%)
• Similarity: 194/432 - (44%)
• Gaps: 34/432 - (7%)

  Fly     4 LFAVVLLLASVALAVENYDGYKIYDINARNAFEKQLLLRLSGNEAYDFFDLPRSLDASSR----- 63
            ||..:|......|....|.|.|:.....:...|...|.::|.....|.:. |.|:...|.
Human    20 LFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQ-PSSISYVSEGTVTD 83

  Fly    64 VMVKPEDQEGFEHLLEKYGVNYSVINENF------GESLRQERDENQNQRLMNLRSAERSVSFKA 122
            |.:...........|::..:.|.|:.|:.      |.||..:|    |:|.::      ..:::.
Human    84 VHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQR----NRRSLS------GYNYEV 138

  Fly   123 FHRHAEINAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWI 187
            :|...||..::..|...:...:.:...|:|||.|.:..:.:  |.....|..|::|.||||||||
Human   139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKL--GRRSRLKRAVWIDCGIHAREWI 201

  Fly   188 AHAGALYVIHQLVENF---AANSELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKPISS-ACY 248
            ..|...:.:.:.:..:   .|..::|....:.|:||.|.|||.:|.|..|.|||||...|. .|.
Human   202 GPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCR 266

  Fly   249 GTDANRNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLL 313
            |.|||||:...|.:.|||.:.|.||:.|....||||.:.:.:.|.......:.||:.|:|...||
Human   267 GVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLL 331

  Fly   314 YPWGWTSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAF--GVANFPV 376
            ||:.:..|...::|..:..|....:|::|..|.:|..|.::..||.::|.|.|:|:  |:   |.
Human   332 YPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGI---PY 393

  Fly   377 SITMEL-PAGGTGFNPSTSQIEGFVSETWVGIKAMAQKVADK 417
            :...|| ..|..||......|:...:||.:.:|.:...:..|
Human   394 AFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKK 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_648120.3	Propep_M14	27..99	CDD:460505	15/82 (18%)
		M14_CP_A-B_like	123..414	CDD:349433	93/297 (31%)
CPA6	NP_065094.3	Propep_M14	43..118	CDD:460505	12/75 (16%)
		M14_CPA6	138..436	CDD:349444	94/303 (31%)