DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8560 and CG8562

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	230/418 - (55%)
Similarity:	294/418 - (70%)	Gaps:	8/418 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VVLLLASVALAVENYDGYKIYDINARNAFEKQLLLRLSGNEAYDFFDLPRSLDASSRVMVKPEDQ 71
            |:.|.|::..|.::|:||:||::....|.:..||.:|| .:.|||....|.|...|||:|.|...
  Fly     9 VLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQLS-LQGYDFISETRLLGHPSRVIVSPAQL 72

  Fly    72 EGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFKAFHRHAEINAYLDEL 136
            :.|:.|:|...:..:::|.|.|.|:.:|..:.|.|||:...:.:..:|.:.::.|.||..|:|:|
  Fly    73 KHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHEEIINYIDDL 137

  Fly   137 AAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWIAHAGALYVIHQLVE 201
            |..:||||.|:..|.|||.|.:|||||||||||..|.|:|:|.|.||||||:.|..||||.||||
  Fly   138 AQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYVIDQLVE 202

  Fly   202 NFAANSELLKDFDWVILPVVNPDGYEYSHTTT--RMWRKTRKPISSA---CYGTDANRNFDFHWG 261
            .|..|:.||||:||||||:||.||||::.|.|  |||||||:|.:.|   |||.|.||||||||.
  Fly   203 QFEENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHWN 267

  Fly   262 EVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWGWTSALPSSW 326
            |.||||..|:||:.|.||||||||..:||::.||..||..|||||||||||||||||||.||.:|
  Fly   268 EEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLLYPWGWTSDLPENW 332

  Fly   327 RDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAFGVANFPVSITMELP-AGGTGFN 390
            .|.|.||:.||:||::||||.||.||||||||.|||.||||.: .|.|.|||||||| ||..|||
  Fly   333 EDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGY-YAGFNVSITMELPGAGSIGFN 396

  Fly   391 PSTSQIEGFVSETWVGIKAMAQKVADKY 418
            |..::|:.||:|||:||:|||:||.:.|
  Fly   397 PPVTRIDEFVTETWIGIRAMAEKVIEMY 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	22/68 (32%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	190/296 (64%)
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	22/69 (32%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	190/296 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450336
Domainoid	1	1.000	342	1.000	Domainoid score	I2903
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	1	1.000	-	-		H76534
Inparanoid	1	1.050	387	1.000	Inparanoid score	I4105
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13580
	13	12.750